Biomolecular magic-angle spinning solid-state NMR: Recent methods and applications

Research output: Contribution to journalReview articlepeer-review


The link of structure and dynamics of biomolecules and their complexes to their function and to many cellular processes has driven the quest for their detailed characterization by a variety of biophysical techniques. Magic-angle spinning solid-state nuclear magnetic resonance spectroscopy provides detailed information on the structural properties of such systems and in particular contributes invaluable information on non-soluble, large molecular-weight and non-crystalline biomolecules. This review summarizes the recent progress that has been made in the characterization of macromolecular assemblies, viruses, membrane proteins, amyloid fibrils, protein aggregates and more by magic-angle spinning solid-state NMR.

Original languageEnglish
Pages (from-to)705-715
Number of pages11
JournalCurrent Opinion in Biotechnology
Issue number4
StatePublished - Aug 2013

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering


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