Bioinformatic approaches for identification of A-to-I editing sites

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The first discoveries of mammalian A-to-I RNA editing have been serendipitous. In conjunction with the fast advancement in sequencing technology, systematic methods for prediction and detection of editing sites have been developed, leading to the discovery of thousands of A-to-I editing sites. Here we review the state-of-the-art of these methods and discuss future directions.

Original languageEnglish
Title of host publicationAdenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
Pages145-162
Number of pages18
Edition1
DOIs
StatePublished - 2012

Publication series

NameCurrent Topics in Microbiology and Immunology
Number1
Volume353

Keywords

  • A-to-I RNA editing
  • Alu repeats
  • Bioinformatics
  • Deep sequencing

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Microbiology
  • Immunology
  • Microbiology (medical)

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