Abstract
The highly diastereo- and enantioselective formation of polysubstituted cyclopropanes was easily achieved through the asymmetric copper-catalyzed carbomagnesiation reaction of nonfunctionalized cyclopropene derivatives. The carbometalated species generated in situ readily undergo C−C and C−X bond-forming reactions with various electrophiles with complete retention of configuration.
Original language | English |
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Pages (from-to) | 6783-6787 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 56 |
Issue number | 24 |
DOIs | |
State | Published - 6 Jun 2017 |
Keywords
- asymmetric catalysis
- carbometalation
- configurational stability
- cyclopropanes
- cyclopropenes
All Science Journal Classification (ASJC) codes
- General Chemistry
- Catalysis