TY - JOUR
T1 - Assigning the right credit to the wrong action
T2 - compulsivity in the general population is associated with augmented outcome-irrelevant value-based learning
AU - Shahar, Nitzan
AU - Hauser, Tobias U.
AU - Moran, Rani
AU - Moutoussis, Michael
AU - Bullmore, Edward
AU - Dolan, Raymond J.
AU - Goodyer, Ian
AU - Fonagy, Peter
AU - Jones, Peter
AU - Moutoussis, Michael
AU - Hauser, Tobias
AU - Neufeld, Sharon
AU - Romero-Garcia, Rafael
AU - Clair, Michelle St
AU - Vértes, Petra
AU - Whitaker, Kirstie
AU - Inkster, Becky
AU - Prabhu, Gita
AU - Ooi, Cinly
AU - Toseeb, Umar
AU - Widmer, Barry
AU - Bhatti, Junaid
AU - Villis, Laura
AU - Alrumaithi, Ayesha
AU - Birt, Sarah
AU - Bowler, Aislinn
AU - Cleridou, Kalia
AU - Dadabhoy, Hina
AU - Davies, Emma
AU - Firkins, Ashlyn
AU - Granville, Sian
AU - Harding, Elizabeth
AU - Hopkins, Alexandra
AU - Isaacs, Daniel
AU - King, Janchai
AU - Kokorikou, Danae
AU - Maurice, Christina
AU - McIntosh, Cleo
AU - Memarzia, Jessica
AU - Mills, Harriet
AU - O’Donnell, Ciara
AU - Pantaleone, Sara
AU - Scott, Jenny
AU - Kiddle, Beatrice
AU - Polek, Ela
AU - Fearon, Pasco
AU - Suckling, John
AU - van Harmelen, Anne Laura
AU - Kievit, Rogier
AU - Chamberlain, Sam
N1 - Publisher Copyright: © 2021, The Author(s).
PY - 2021/12
Y1 - 2021/12
N2 - Compulsive behavior is enacted under a belief that a specific act controls the likelihood of an undesired future event. Compulsive behaviors are widespread in the general population despite having no causal relationship with events they aspire to influence. In the current study, we tested whether there is an increased tendency to assign value to aspects of a task that do not predict an outcome (i.e., outcome-irrelevant learning) among individuals with compulsive tendencies. We studied 514 healthy individuals who completed self-report compulsivity, anxiety, depression, and schizotypal measurements, and a well-established reinforcement-learning task (i.e., the two-step task). As expected, we found a positive relationship between compulsivity and outcome-irrelevant learning. Specifically, individuals who reported having stronger compulsive tendencies (e.g., washing, checking, grooming) also tended to assign value to response keys and stimuli locations that did not predict an outcome. Controlling for overall goal-directed abilities and the co-occurrence of anxious, depressive, or schizotypal tendencies did not impact these associations. These findings indicate that outcome-irrelevant learning processes may contribute to the expression of compulsivity in a general population setting. We highlight the need for future research on the formation of non-veridical action−outcome associations as a factor related to the occurrence and maintenance of compulsive behavior.
AB - Compulsive behavior is enacted under a belief that a specific act controls the likelihood of an undesired future event. Compulsive behaviors are widespread in the general population despite having no causal relationship with events they aspire to influence. In the current study, we tested whether there is an increased tendency to assign value to aspects of a task that do not predict an outcome (i.e., outcome-irrelevant learning) among individuals with compulsive tendencies. We studied 514 healthy individuals who completed self-report compulsivity, anxiety, depression, and schizotypal measurements, and a well-established reinforcement-learning task (i.e., the two-step task). As expected, we found a positive relationship between compulsivity and outcome-irrelevant learning. Specifically, individuals who reported having stronger compulsive tendencies (e.g., washing, checking, grooming) also tended to assign value to response keys and stimuli locations that did not predict an outcome. Controlling for overall goal-directed abilities and the co-occurrence of anxious, depressive, or schizotypal tendencies did not impact these associations. These findings indicate that outcome-irrelevant learning processes may contribute to the expression of compulsivity in a general population setting. We highlight the need for future research on the formation of non-veridical action−outcome associations as a factor related to the occurrence and maintenance of compulsive behavior.
UR - http://www.scopus.com/inward/record.url?scp=85121946695&partnerID=8YFLogxK
U2 - https://doi.org/10.1038/s41398-021-01642-x
DO - https://doi.org/10.1038/s41398-021-01642-x
M3 - مقالة
C2 - 34741013
SN - 2158-3188
VL - 11
JO - Translational Psychiatry
JF - Translational Psychiatry
IS - 1
M1 - 564
ER -