Assessment of tissue perfusion in the lower limbs using laser speckle analysis

Mark Golberg, Ran Califa, Sagi Polani, Orit Goldstein, Zailer Aviram, Meir Niska, Zeev Zalevsky

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Diabetic foot is a well-known problem among patients suffering from peripheral arterial diseases (PAD). An optical sensor was built for a contactless measurement of the anatomical site, composing of a diode-laser and a high-speed camera. The laser illuminates the inspected tissue and the back reflected light forms time changing speckle patterns. We used second order autocorrelation function (ACF) decay time as merit for blood flow estimation. Clinical study with 15 subjects was conducted. An occlusion test was introduced to provoke a statistical parameter to distinguish between low perfused and a healthy foot.

Original languageEnglish
Title of host publicationDynamics and Fluctuations in Biomedical Photonics XVIII
EditorsValery V. Tuchin, Martin J. Leahy, Ruikang K. Wang
PublisherSPIE
ISBN (Electronic)9781510641174
DOIs
StatePublished - 2021
EventDynamics and Fluctuations in Biomedical Photonics XVIII 2021 - Virtual, Online, United States
Duration: 6 Mar 202111 Mar 2021

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11641

Conference

ConferenceDynamics and Fluctuations in Biomedical Photonics XVIII 2021
Country/TerritoryUnited States
CityVirtual, Online
Period6/03/2111/03/21

Keywords

  • Diabetic foot
  • Dynamic laser speckles

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging
  • Biomaterials

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