Applications of Magnetic-Responsive Materials for Cardiovascular Tissue Engineering

Lindsay Steele, Gal Margolis, Smadar Cohen, Boris Polyak

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Cardiovascular tissue engineering (CTE) aims to provide regenerative solutions in the creation of contractile and vascularized tissues capable of replacing damaged or dysfunctional myocardium. Additionally, CTE aims to offer cell-based strategies to regenerate injured arteries and heal vascular lesions, mitigating the complications of an obstructive coronary vascular disease, the key factor leading to an acute myocardial infarction and heart failure. Magnetic-responsive biomaterials in the form of scaffolds or nanoparticles offer unique opportunities to create stimulatory conditions or means for efficient cell delivery, as a part of multi-component microenvironment promoting tissue development and regeneration in vitro and in vivo. This chapter will discuss strategies and principles that leverage the unique properties of magnetic materials, enabling the creation of functional and vascularized tissue constructs, generating directionally-guided tissue structures, and forming physical means for efficient delivery, homing and engraftment of cell-based therapies in cardiovascular applications.

Original languageAmerican English
Title of host publicationSelf-Cleaning Coatings
Subtitle of host publicationStructure, Fabrication and Application
EditorsQun Wang
PublisherRoyal Society of Chemistry
Number of pages39
StatePublished - 1 Jan 2017

Publication series

NameRSC Smart Materials

All Science Journal Classification (ASJC) codes

  • Energy Engineering and Power Technology
  • Electrical and Electronic Engineering
  • Biotechnology
  • Biomedical Engineering
  • General Materials Science


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