APPI-Derived Cyclic Peptide Enhances Aβ42 Aggregation and Reduces Aβ42-Mediated Membrane Destabilization and Cytotoxicity

Medicine & Life Sciences

• Alzheimer Disease 8%
• Amino Acid Sequence 4%
• Amyloid 66%
• amyloid beta-protein (1-42) 14%
• Amyloid beta-Protein Precursor 80%
• amyloid beta-protein precursor inhibitor 11%
• Apoptosis 3%
• Brain 2%
• Cell Death 4%
• Cell Membrane 3%
• Cyclic Peptides 100%
• Membranes 41%
• Mitochondrial Membranes 11%
• Molecular Weight 13%
• Phospholipids 4%
• Therapeutics 0%

Chemistry

• Amino Acid Sequence 4%
• Beta-Amyloid 78%
• Cell Death 4%
• Cyclic Peptide 81%
• Depolarization 5%
• Neurotoxic 5%
• Oligomer 3%
• Peptide 5%
• Phospholipid 3%
• Plasma 2%
• Protein 28%