Antagonistic Activity of Naphthoquinone-Based Hybrids toward Amyloids Associated with Alzheimer's Disease and Type-2 Diabetes

Medicine & Life Sciences

• Naphthoquinones 100%
• Alzheimer disease type 2 97%
• Amyloid 60%
• Type 2 Diabetes Mellitus 48%
• Amyloidogenic Proteins 34%
• peptide A42 29%
• thioflavin T 18%
• Islet Amyloid Polypeptide 17%
• Hydrogen Bonding 15%
• Hydrophobic and Hydrophilic Interactions 14%
• Sequence Homology 14%
• Tryptophan 13%
• Spectrum Analysis 12%
• Computer Simulation 12%
• Psychology Recognition 11%
• Electron Microscopy 11%
• Parkinson Disease 10%
• Coloring Agents 10%
• Psychological Inhibition 10%
• Alzheimer Disease 9%
• Membranes 7%
• In Vitro Techniques 5%
• Proteins 4%
• Therapeutics 4%

Chemistry

• Molecule 22%
• Naphthoquinone 16%
• Protein 15%
• Amyloid Fibril 15%
• Electron Microscopy 11%
• Polypeptide 10%
• Spectroscopy 8%
• Dye 7%
• Hydrogen Bond 7%
• Peptide 7%