An infant with a diagnostically challenging hepatic teratoma, hypofibrinogenemia, and adrenal neuroblastoma: Case report

Iris Fried; Eitan Rom-Gross; Milton Finegold; Natalia Simanovsky; Shoshana Revel-Vilk; Ziva Ben-Neriah; Michael Weintraub; Orit Pappo; Karen Meir

doi:10.2350/13-08-1361-CR.1

An infant with a diagnostically challenging hepatic teratoma, hypofibrinogenemia, and adrenal neuroblastoma: Case report

Iris Fried, Eitan Rom-Gross, Milton Finegold, Natalia Simanovsky, Shoshana Revel-Vilk, Ziva Ben-Neriah, Michael Weintraub, Orit Pappo, Karen Meir

Research output: Contribution to journal › Article › peer-review

Abstract

Teratomas of the liver are exceedingly rare. Neuroblastoma is the most common, extracranial solid tumor of infancy. We describe the case of a 2-month-old, female infant who presented with an abdominal mass arising in the right lobe of the liver, and a severe coagulopathy, which necessitated cryoprecipitate infusion. Biopsy was interpreted as hepatoblastoma. Following resection, difficulty classifying the mass led to several consultations, and an eventual diagnosis of teratoma. During follow-up, the patient was diagnosed with right adrenal neuroblastoma, which, in retrospect, had been present before the hepatic resection. To our knowledge, these 2 tumors have never been reported together, or in combination with isolated hypofibrinogenemia.

Original language	English
Pages (from-to)	251-256
Number of pages	6
Journal	Pediatric and Developmental Pathology
Volume	18
Issue number	3
DOIs	https://doi.org/10.2350/13-08-1361-CR.1
State	Published - 1 May 2015
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Hepatoblastoma
Hypofibrinogenemia
Liver tumor
Neuroblastoma
Teratoma

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Pathology and Forensic Medicine

Access to Document

10.2350/13-08-1361-CR.1

Cite this

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title = "An infant with a diagnostically challenging hepatic teratoma, hypofibrinogenemia, and adrenal neuroblastoma: Case report",

abstract = "Teratomas of the liver are exceedingly rare. Neuroblastoma is the most common, extracranial solid tumor of infancy. We describe the case of a 2-month-old, female infant who presented with an abdominal mass arising in the right lobe of the liver, and a severe coagulopathy, which necessitated cryoprecipitate infusion. Biopsy was interpreted as hepatoblastoma. Following resection, difficulty classifying the mass led to several consultations, and an eventual diagnosis of teratoma. During follow-up, the patient was diagnosed with right adrenal neuroblastoma, which, in retrospect, had been present before the hepatic resection. To our knowledge, these 2 tumors have never been reported together, or in combination with isolated hypofibrinogenemia.",

keywords = "Hepatoblastoma, Hypofibrinogenemia, Liver tumor, Neuroblastoma, Teratoma",

author = "Iris Fried and Eitan Rom-Gross and Milton Finegold and Natalia Simanovsky and Shoshana Revel-Vilk and Ziva Ben-Neriah and Michael Weintraub and Orit Pappo and Karen Meir",

note = "Publisher Copyright: {\textcopyright} 2015 Society for Pediatric Pathology.",

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doi = "10.2350/13-08-1361-CR.1",

language = "الإنجليزيّة",

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T1 - An infant with a diagnostically challenging hepatic teratoma, hypofibrinogenemia, and adrenal neuroblastoma

T2 - Case report

AU - Fried, Iris

AU - Rom-Gross, Eitan

AU - Finegold, Milton

AU - Simanovsky, Natalia

AU - Revel-Vilk, Shoshana

AU - Ben-Neriah, Ziva

AU - Weintraub, Michael

AU - Pappo, Orit

AU - Meir, Karen

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Teratomas of the liver are exceedingly rare. Neuroblastoma is the most common, extracranial solid tumor of infancy. We describe the case of a 2-month-old, female infant who presented with an abdominal mass arising in the right lobe of the liver, and a severe coagulopathy, which necessitated cryoprecipitate infusion. Biopsy was interpreted as hepatoblastoma. Following resection, difficulty classifying the mass led to several consultations, and an eventual diagnosis of teratoma. During follow-up, the patient was diagnosed with right adrenal neuroblastoma, which, in retrospect, had been present before the hepatic resection. To our knowledge, these 2 tumors have never been reported together, or in combination with isolated hypofibrinogenemia.

AB - Teratomas of the liver are exceedingly rare. Neuroblastoma is the most common, extracranial solid tumor of infancy. We describe the case of a 2-month-old, female infant who presented with an abdominal mass arising in the right lobe of the liver, and a severe coagulopathy, which necessitated cryoprecipitate infusion. Biopsy was interpreted as hepatoblastoma. Following resection, difficulty classifying the mass led to several consultations, and an eventual diagnosis of teratoma. During follow-up, the patient was diagnosed with right adrenal neuroblastoma, which, in retrospect, had been present before the hepatic resection. To our knowledge, these 2 tumors have never been reported together, or in combination with isolated hypofibrinogenemia.

KW - Hepatoblastoma

KW - Hypofibrinogenemia

KW - Liver tumor

KW - Neuroblastoma

KW - Teratoma

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U2 - 10.2350/13-08-1361-CR.1

DO - 10.2350/13-08-1361-CR.1

M3 - مقالة

C2 - 25756389

SN - 1093-5266

VL - 18

SP - 251

EP - 256

JO - Pediatric and Developmental Pathology

JF - Pediatric and Developmental Pathology

IS - 3

ER -

An infant with a diagnostically challenging hepatic teratoma, hypofibrinogenemia, and adrenal neuroblastoma: Case report

Abstract

UN SDGs

Keywords

All Science Journal Classification (ASJC) codes

Access to Document

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