Amplification of chiroptical activity of chiral biomolecules by surface plasmons

Ben M. Maoz; Yulia Chaikin; Alexander B. Tesler; Omri Bar Elli; Zhiyuan Fan; Alexander O. Govorov; Gil Markovich

doi:10.1021/nl304638a

Amplification of chiroptical activity of chiral biomolecules by surface plasmons

Ben M. Maoz, Yulia Chaikin, Alexander B. Tesler, Omri Bar Elli, Zhiyuan Fan, Alexander O. Govorov, Gil Markovich

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

Chiral molecules are shown to induce circular dichroism (CD) at surface plasmon resonances of gold nanostructures when in proximity to the metal surface without direct bonding to the metal. By changing the molecule-Au separation, we were able to learn about the mechanism of plasmonic CD induction for such nanostructures. It was found that even two monolayers of chiral molecules can induce observable plasmonic CD, while without the presence of the plasmonic nanostructures their own CD signal is unmeasurable. Hence, plasmonic arrays could offer a route to enhanced sensitivity for chirality detection.

Original language	English
Pages (from-to)	1203-1209
Number of pages	7
Journal	Nano Letters
Volume	13
Issue number	3
DOIs	https://doi.org/10.1021/nl304638a
State	Published - 13 Mar 2013

Keywords

Gold nanoparticles
biosensing
chirality
circular dichroism
surface plasmon resonance

All Science Journal Classification (ASJC) codes

Bioengineering
General Chemistry
General Materials Science
Condensed Matter Physics
Mechanical Engineering

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10.1021/nl304638a

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title = "Amplification of chiroptical activity of chiral biomolecules by surface plasmons",

abstract = "Chiral molecules are shown to induce circular dichroism (CD) at surface plasmon resonances of gold nanostructures when in proximity to the metal surface without direct bonding to the metal. By changing the molecule-Au separation, we were able to learn about the mechanism of plasmonic CD induction for such nanostructures. It was found that even two monolayers of chiral molecules can induce observable plasmonic CD, while without the presence of the plasmonic nanostructures their own CD signal is unmeasurable. Hence, plasmonic arrays could offer a route to enhanced sensitivity for chirality detection.",

keywords = "Gold nanoparticles, biosensing, chirality, circular dichroism, surface plasmon resonance",

author = "Maoz, \{Ben M.\} and Yulia Chaikin and Tesler, \{Alexander B.\} and \{Bar Elli\}, Omri and Zhiyuan Fan and Govorov, \{Alexander O.\} and Gil Markovich",

note = "Israel Science Foundation [172/10]; James Frank program on light-matter interaction; NSF (USA); Tel Aviv University Center for Nanoscience and NanotechnologyThis research was supported by the Israel Science Foundation grant no. 172/10, the James Frank program on light-matter interaction, and NSF (USA). The authors are grateful to Ofer Kedem for fruitful discussions and Alexander Vaskevich and Israel Rubinstein for their support of this work. B.M.M. was supported by The Tel Aviv University Center for Nanoscience and Nanotechnology.",

year = "2013",

month = mar,

day = "13",

doi = "10.1021/nl304638a",

language = "الإنجليزيّة",

volume = "13",

pages = "1203--1209",

journal = "Nano Letters",

issn = "1530-6984",

publisher = "American Chemical Society",

number = "3",

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TY - JOUR

T1 - Amplification of chiroptical activity of chiral biomolecules by surface plasmons

AU - Maoz, Ben M.

AU - Chaikin, Yulia

AU - Tesler, Alexander B.

AU - Bar Elli, Omri

AU - Fan, Zhiyuan

AU - Govorov, Alexander O.

AU - Markovich, Gil

N1 - Israel Science Foundation [172/10]; James Frank program on light-matter interaction; NSF (USA); Tel Aviv University Center for Nanoscience and NanotechnologyThis research was supported by the Israel Science Foundation grant no. 172/10, the James Frank program on light-matter interaction, and NSF (USA). The authors are grateful to Ofer Kedem for fruitful discussions and Alexander Vaskevich and Israel Rubinstein for their support of this work. B.M.M. was supported by The Tel Aviv University Center for Nanoscience and Nanotechnology.

PY - 2013/3/13

Y1 - 2013/3/13

N2 - Chiral molecules are shown to induce circular dichroism (CD) at surface plasmon resonances of gold nanostructures when in proximity to the metal surface without direct bonding to the metal. By changing the molecule-Au separation, we were able to learn about the mechanism of plasmonic CD induction for such nanostructures. It was found that even two monolayers of chiral molecules can induce observable plasmonic CD, while without the presence of the plasmonic nanostructures their own CD signal is unmeasurable. Hence, plasmonic arrays could offer a route to enhanced sensitivity for chirality detection.

AB - Chiral molecules are shown to induce circular dichroism (CD) at surface plasmon resonances of gold nanostructures when in proximity to the metal surface without direct bonding to the metal. By changing the molecule-Au separation, we were able to learn about the mechanism of plasmonic CD induction for such nanostructures. It was found that even two monolayers of chiral molecules can induce observable plasmonic CD, while without the presence of the plasmonic nanostructures their own CD signal is unmeasurable. Hence, plasmonic arrays could offer a route to enhanced sensitivity for chirality detection.

KW - Gold nanoparticles

KW - biosensing

KW - chirality

KW - circular dichroism

KW - surface plasmon resonance

UR - http://www.scopus.com/inward/record.url?scp=84874959637&partnerID=8YFLogxK

U2 - 10.1021/nl304638a

DO - 10.1021/nl304638a

M3 - مقالة

SN - 1530-6984

VL - 13

SP - 1203

EP - 1209

JO - Nano Letters

JF - Nano Letters

IS - 3

ER -

Amplification of chiroptical activity of chiral biomolecules by surface plasmons

Abstract

Keywords

All Science Journal Classification (ASJC) codes

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