Alginate biomaterials for the treatment of hepatic disorders

Yaron Ilan (Inventor), Gadi Lalazar (Inventor), Eyal Shteyer (Inventor), Ami Ben-Ya'acov (Inventor), Smadar Cohen (Inventor), Tsiona Elkayam (Inventor)

Research output: Patent


The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention are based on the administration, preferably, systemic administration, of a therapeutically effective amount of at least one biocompatible alginate biomaterial, any modification thereof and any combination thereof. The invention further provides methods for sustaining serum albumin levels, and/or reducing serum AST and ALT, in subjects suffering from hepatic disorder. Still further, the invention provides methods for reducing apoptosis and inducing cell proliferation in a damaged liver tissue of a subject suffering of hepatic disorder, using the alginate biomaterial described by the invention.
Original languageEnglish
Patent numberUS10328098B2
StatePublished - 1 Jun 2019


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