AFFINITY ENTITIES COMPRISING A TCR-LIKE ANTIBODY BINDING DOMAIN WITH HIGH AFFINITY AND FINE SPECIFICITY AND USES OF SAME

Mira Peled Kamar (Inventor), Galit Denkberg (Inventor), Yoram Reiter (Inventor), Ilan Beer (Inventor), Keren Sinik (Inventor), Yael Teboul (Elbaz) (Inventor), Yael Shperber (Sery) (Inventor), Reut Erel Segal (Inventor), Ravit Oren (Inventor), Mira Peled Kamar (Inventor), Galit Denkberg (Inventor), Yoram Reiter (Inventor), IIan Beer (Inventor), Keren Sinik (Inventor), Yael Teboul (elbaz) (Inventor), Yael Shperber (sery) (Inventor), Reut Erel Segal (Inventor), Ravit Oren (Inventor), Dror Shmuel Alishekevitz (Inventor), Dror Shmuel Alishekevitz (Inventor)

Research output: Patent

Abstract

Affinity binding entities having TCRL binding domain and methods of their use are provided. More specifically these compositions bind HLA-A2/WT1+, HLA-A2/MAGE-A4, HLA-A2/MAGE-A9, HLA-A2/PAP or HLA-A2/TyrD+ cells and as such can be used in diagnostics and therapy.

Original languageAmerican English
Patent numberUS2018171024 AA
IPCG01N 33/ 574 A I
Priority date8/06/16
StatePublished - 21 Jun 2018

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