A versatile water-soluble chelating and radical scavenging platform

Meital Eckshtain-Levi; Ronit Lavi; Dmitry S. Yufit; Bareket Daniel; Omer Green; Ohad Fleker; Michal Richman; Shai Rahimipour; Arie Gruzman; Laurent Benisvy

doi:10.1039/c5cc08198j

A versatile water-soluble chelating and radical scavenging platform

Meital Eckshtain-Levi, Ronit Lavi, Dmitry S. Yufit, Bareket Daniel, Omer Green, Ohad Fleker, Michal Richman, Shai Rahimipour, Arie Gruzman, Laurent Benisvy

Bar-Ilan University

Research output: Contribution to journal › Article › peer-review

Abstract

The phenol-diamide compound, 5-(tert-butyl)-2-hydroxy-N1,N3-bis(2-hydroxyethyl)isophthalamide (1OH), is water-soluble, non-cytotoxic, and capable of both, trapping ROS species and chelating Cu(ii) and Fe(iii) ions; these combined properties confer a protective effect against ROS induced cell death.

Original language	English
Pages (from-to)	2350-2353
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	11
DOIs	https://doi.org/10.1039/c5cc08198j
State	Published - 7 Feb 2016

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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10.1039/c5cc08198j

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title = "A versatile water-soluble chelating and radical scavenging platform",

abstract = "The phenol-diamide compound, 5-(tert-butyl)-2-hydroxy-N1,N3-bis(2-hydroxyethyl)isophthalamide (1OH), is water-soluble, non-cytotoxic, and capable of both, trapping ROS species and chelating Cu(ii) and Fe(iii) ions; these combined properties confer a protective effect against ROS induced cell death.",

author = "Meital Eckshtain-Levi and Ronit Lavi and Yufit, {Dmitry S.} and Bareket Daniel and Omer Green and Ohad Fleker and Michal Richman and Shai Rahimipour and Arie Gruzman and Laurent Benisvy",

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T1 - A versatile water-soluble chelating and radical scavenging platform

AU - Eckshtain-Levi, Meital

AU - Lavi, Ronit

AU - Yufit, Dmitry S.

AU - Daniel, Bareket

AU - Green, Omer

AU - Fleker, Ohad

AU - Richman, Michal

AU - Rahimipour, Shai

AU - Gruzman, Arie

AU - Benisvy, Laurent

PY - 2016/2/7

Y1 - 2016/2/7

N2 - The phenol-diamide compound, 5-(tert-butyl)-2-hydroxy-N1,N3-bis(2-hydroxyethyl)isophthalamide (1OH), is water-soluble, non-cytotoxic, and capable of both, trapping ROS species and chelating Cu(ii) and Fe(iii) ions; these combined properties confer a protective effect against ROS induced cell death.

AB - The phenol-diamide compound, 5-(tert-butyl)-2-hydroxy-N1,N3-bis(2-hydroxyethyl)isophthalamide (1OH), is water-soluble, non-cytotoxic, and capable of both, trapping ROS species and chelating Cu(ii) and Fe(iii) ions; these combined properties confer a protective effect against ROS induced cell death.

UR - http://www.scopus.com/inward/record.url?scp=84956634400&partnerID=8YFLogxK

U2 - 10.1039/c5cc08198j

DO - 10.1039/c5cc08198j

M3 - مقالة

C2 - 26731129

SN - 1359-7345

VL - 52

SP - 2350

EP - 2353

JO - Chemical Communications

JF - Chemical Communications

IS - 11

ER -

A versatile water-soluble chelating and radical scavenging platform

Abstract

All Science Journal Classification (ASJC) codes

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