A novel method for hydrogel nanostructuring

Ortal Yom-Tov; Ilya Frisman; Dror Seliktar; Havazelet Bianco-Peled

doi:10.1016/j.eurpolymj.2014.01.004

A novel method for hydrogel nanostructuring

Ortal Yom-Tov, Ilya Frisman, Dror Seliktar, Havazelet Bianco-Peled

Technion - Israel Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

Nanostructured hydrogels tailor-made for specific applications are new grounds for the creation of novel soft materials. The current research presents a new method for hydrogel nanostructuring involving the incorporation of Pluronic® F127 micelles mixed with acrylated blockcopolymer molecules, which enable the attachment of these micelles to the hydrogel matrix through their endgroups. This design impacts the hydrogel nanostructure as well as its swelling and mechanical properties. Small Angle X-ray Scattering (SAXS) and Cryogenic Transmission Electron Microscopy (cryo-TEM) revealed that photochemical crosslinking of the hydrogel caused immobilization of the nanostructured micelles. Mechanical and weight gain experiments demonstrated a significant impact of these nanostructures on the hydrogel's elastic modulus as well as the transient and equilibrium weight gain ability of the material.

Original language	English
Pages (from-to)	137-145
Number of pages	9
Journal	European Polymer Journal
Volume	52
Issue number	1
DOIs	https://doi.org/10.1016/j.eurpolymj.2014.01.004
State	Published - Mar 2014

Keywords

Hydrogel
Nanostructuring
SAXS
Structure

All Science Journal Classification (ASJC) codes

Materials Chemistry
Polymers and Plastics
General Physics and Astronomy
Organic Chemistry

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10.1016/j.eurpolymj.2014.01.004

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title = "A novel method for hydrogel nanostructuring",

abstract = "Nanostructured hydrogels tailor-made for specific applications are new grounds for the creation of novel soft materials. The current research presents a new method for hydrogel nanostructuring involving the incorporation of Pluronic{\textregistered} F127 micelles mixed with acrylated blockcopolymer molecules, which enable the attachment of these micelles to the hydrogel matrix through their endgroups. This design impacts the hydrogel nanostructure as well as its swelling and mechanical properties. Small Angle X-ray Scattering (SAXS) and Cryogenic Transmission Electron Microscopy (cryo-TEM) revealed that photochemical crosslinking of the hydrogel caused immobilization of the nanostructured micelles. Mechanical and weight gain experiments demonstrated a significant impact of these nanostructures on the hydrogel's elastic modulus as well as the transient and equilibrium weight gain ability of the material.",

keywords = "Hydrogel, Nanostructuring, SAXS, Structure",

author = "Ortal Yom-Tov and Ilya Frisman and Dror Seliktar and Havazelet Bianco-Peled",

note = "Funding Information: This research was supported by the Singapore National Research Foundation under CREATE programme: The Regenerative Medicine Initiative in Cardiac Restoration Therapy (NRF-Technion).",

year = "2014",

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doi = "10.1016/j.eurpolymj.2014.01.004",

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AU - Yom-Tov, Ortal

AU - Frisman, Ilya

AU - Seliktar, Dror

AU - Bianco-Peled, Havazelet

N1 - Funding Information: This research was supported by the Singapore National Research Foundation under CREATE programme: The Regenerative Medicine Initiative in Cardiac Restoration Therapy (NRF-Technion).

PY - 2014/3

Y1 - 2014/3

N2 - Nanostructured hydrogels tailor-made for specific applications are new grounds for the creation of novel soft materials. The current research presents a new method for hydrogel nanostructuring involving the incorporation of Pluronic® F127 micelles mixed with acrylated blockcopolymer molecules, which enable the attachment of these micelles to the hydrogel matrix through their endgroups. This design impacts the hydrogel nanostructure as well as its swelling and mechanical properties. Small Angle X-ray Scattering (SAXS) and Cryogenic Transmission Electron Microscopy (cryo-TEM) revealed that photochemical crosslinking of the hydrogel caused immobilization of the nanostructured micelles. Mechanical and weight gain experiments demonstrated a significant impact of these nanostructures on the hydrogel's elastic modulus as well as the transient and equilibrium weight gain ability of the material.

AB - Nanostructured hydrogels tailor-made for specific applications are new grounds for the creation of novel soft materials. The current research presents a new method for hydrogel nanostructuring involving the incorporation of Pluronic® F127 micelles mixed with acrylated blockcopolymer molecules, which enable the attachment of these micelles to the hydrogel matrix through their endgroups. This design impacts the hydrogel nanostructure as well as its swelling and mechanical properties. Small Angle X-ray Scattering (SAXS) and Cryogenic Transmission Electron Microscopy (cryo-TEM) revealed that photochemical crosslinking of the hydrogel caused immobilization of the nanostructured micelles. Mechanical and weight gain experiments demonstrated a significant impact of these nanostructures on the hydrogel's elastic modulus as well as the transient and equilibrium weight gain ability of the material.

KW - Hydrogel

KW - Nanostructuring

KW - SAXS

KW - Structure

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U2 - 10.1016/j.eurpolymj.2014.01.004

DO - 10.1016/j.eurpolymj.2014.01.004

M3 - مقالة

SN - 0014-3057

VL - 52

SP - 137

EP - 145

JO - European Polymer Journal

JF - European Polymer Journal

IS - 1

ER -

A novel method for hydrogel nanostructuring

Abstract

Keywords

All Science Journal Classification (ASJC) codes

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