A new diagnostic tool based on diffusion reflection measurements of gold nanoparticles

Rinat Ankri; Hamootal Duadi; Dror Fixler

doi:10.1117/12.908789

A new diagnostic tool based on diffusion reflection measurements of gold nanoparticles

Rinat Ankri
, Hamootal Duadi
, Dror Fixler

Bar-Ilan University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The ability to quantitatively and non-invasively detect nanoparticles in tissues has important implications on their development as an in-vivo cancer diagnostic tool. The Diffusion Reflection (DR) method is a simple, non-invasive imaging technique which has been proven useful for the investigation of tissue's optical parameters. We present a new method for the measurements of the GNR concentration in tissue-like phantoms based on DR measurements and the intense light absorption of gold nanorods (GNR). Monte Carlo simulations and tissue-like phantom measurements of the reflected light intensity are presented. The ability to extract the phantoms' optical properties and the GNR concentration in it from DR measurements was demonstrated.

Original language	English
Title of host publication	Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X
DOIs	https://doi.org/10.1117/12.908789
State	Published - 2012
Event	Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X - San Francisco, CA, United States Duration: 21 Jan 2012 → 23 Jan 2012

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8225

Conference

Conference	Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X
Country/Territory	United States
City	San Francisco, CA
Period	21/01/12 → 23/01/12

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Diffusion Reflection
Gold Nanorods
Monte-Carlo Simulations
Tissue-like Phantoms

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.908789

Cite this

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title = "A new diagnostic tool based on diffusion reflection measurements of gold nanoparticles",

abstract = "The ability to quantitatively and non-invasively detect nanoparticles in tissues has important implications on their development as an in-vivo cancer diagnostic tool. The Diffusion Reflection (DR) method is a simple, non-invasive imaging technique which has been proven useful for the investigation of tissue's optical parameters. We present a new method for the measurements of the GNR concentration in tissue-like phantoms based on DR measurements and the intense light absorption of gold nanorods (GNR). Monte Carlo simulations and tissue-like phantom measurements of the reflected light intensity are presented. The ability to extract the phantoms' optical properties and the GNR concentration in it from DR measurements was demonstrated.",

keywords = "Diffusion Reflection, Gold Nanorods, Monte-Carlo Simulations, Tissue-like Phantoms",

author = "Rinat Ankri and Hamootal Duadi and Dror Fixler",

year = "2012",

doi = "10.1117/12.908789",

language = "الإنجليزيّة",

isbn = "9780819488688",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

booktitle = "Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X",

note = "Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X ; Conference date: 21-01-2012 Through 23-01-2012",

}

Ankri, R, Duadi, H & Fixler, D 2012, A new diagnostic tool based on diffusion reflection measurements of gold nanoparticles. in Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X., 82250L, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8225, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X, San Francisco, CA, United States, 21/01/12. https://doi.org/10.1117/12.908789

A new diagnostic tool based on diffusion reflection measurements of gold nanoparticles. / Ankri, Rinat; Duadi, Hamootal; Fixler, Dror.
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X. 2012. 82250L (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8225).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Duadi, Hamootal

AU - Fixler, Dror

PY - 2012

Y1 - 2012

N2 - The ability to quantitatively and non-invasively detect nanoparticles in tissues has important implications on their development as an in-vivo cancer diagnostic tool. The Diffusion Reflection (DR) method is a simple, non-invasive imaging technique which has been proven useful for the investigation of tissue's optical parameters. We present a new method for the measurements of the GNR concentration in tissue-like phantoms based on DR measurements and the intense light absorption of gold nanorods (GNR). Monte Carlo simulations and tissue-like phantom measurements of the reflected light intensity are presented. The ability to extract the phantoms' optical properties and the GNR concentration in it from DR measurements was demonstrated.

AB - The ability to quantitatively and non-invasively detect nanoparticles in tissues has important implications on their development as an in-vivo cancer diagnostic tool. The Diffusion Reflection (DR) method is a simple, non-invasive imaging technique which has been proven useful for the investigation of tissue's optical parameters. We present a new method for the measurements of the GNR concentration in tissue-like phantoms based on DR measurements and the intense light absorption of gold nanorods (GNR). Monte Carlo simulations and tissue-like phantom measurements of the reflected light intensity are presented. The ability to extract the phantoms' optical properties and the GNR concentration in it from DR measurements was demonstrated.

KW - Diffusion Reflection

KW - Gold Nanorods

KW - Monte-Carlo Simulations

KW - Tissue-like Phantoms

UR - https://www.scopus.com/pages/publications/84859070508

U2 - 10.1117/12.908789

DO - 10.1117/12.908789

M3 - منشور من مؤتمر

SN - 9780819488688

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X

T2 - Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X

Y2 - 21 January 2012 through 23 January 2012

ER -

A new diagnostic tool based on diffusion reflection measurements of gold nanoparticles

Abstract

Publication series

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this