@inbook{a731effbf1554ed6bd845ce826838e0a,
title = "A Close Encounter of the Third Kind. Monocyte-Derived Cells: Monocyte-Derived Cells",
abstract = "Recent insights into discrete myeloid developmental pathways have provided critical information about the organization of the murine mononuclear phagocyte compartment. Short-lived dendritic cells (DCs) have been shown to continuously arise from dedicated bone marrow-derived precursors. In contrast, it is now appreciated that most tissue macrophage populations are established before birth and subsequently maintain themselves throughout adulthood by longevity and limited self-renewal. Both of these classical tissue-resident mononuclear phagocyte compartments can be complemented on demand by monocyte infiltrates giving rise to macrophage or DC-like cells, depending on the tissue context they encounter upon extravasation. Monocytes hence have emerged as a versatile emergency squad that can be rapidly recruited to sites of injury to provide a transient supplement with proinflammatory or resolving activities for local mononuclear phagocytes.",
keywords = "Dendritic cells, Macrophages, Monocytes",
author = "Alexander Mildner and Simon Yona and Steffen Jung",
note = "Funding Information: This work was supported by the Deutsche Forschungsgemeinschaft (DFG) Research Unit (FOR) 1336. S.J. is a Helmsley Scholar at the Crohn{\textquoteright}s & Colitis Foundation of America. A.M. was a fellow of the Minerva Foundation.",
year = "2013",
doi = "https://doi.org/10.1016/B978-0-12-417028-5.00003-X",
language = "الإنجليزيّة",
series = "Advances in Immunology",
publisher = "Academic Press Inc.",
pages = "69--103",
booktitle = "Advances in Immunology",
address = "الولايات المتّحدة",
}