A cistrome roadmap for understanding pancreatic islet biology

Dana Avrahami, Klaus H. Kaestner

Research output: Contribution to journalReview articlepeer-review


Although dozens of common variants have been associated with increased risk of type 2 diabetes (T2D), the mechanisms by which these variants increase disease susceptibility are largely unknown. A new study mapping the human pancreatic islet cistrome provides a roadmap for exploring the effects of these variants and suggests that altered enhancer function might be a common contributor to the genetic risk of T2D.

Original languageAmerican English
Pages (from-to)95-96
Number of pages2
JournalNature Genetics
Issue number2
StatePublished - Feb 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics


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