A brief review of single-cell transcriptomic technologies

Tomer Kalisky; Sarit Oriel; Tali Hana Bar-Lev; Nissim Ben-Haim; Ariel Trink; Yishay Wineberg; Itamar Kanter; Shlomit Gilad; Saumyadipta Pyne

doi:https://doi.org/10.1093/bfgp/elx019

A brief review of single-cell transcriptomic technologies

Tomer Kalisky, Sarit Oriel, Tali Hana Bar-Lev, Nissim Ben-Haim, Ariel Trink, Yishay Wineberg, Itamar Kanter, Shlomit Gilad, Saumyadipta Pyne

Bar-Ilan University, Weizmann Institute of Science

Research output: Contribution to journal › Review article › peer-review

Abstract

In recent years, there has been an effort to develop new technologies formeasuring gene expression and sequence information fromthousands of individual cells. Large data sets that were obtained using these 'single cell' technologies have allowed scientists to address fundamental questions in biomedicine ranging fromstems cells and development to cancer and immunology. Here, we provide a brief review of recent developments in single-cell technology. Our intention is to provide a quick background for newcomers to the field as well as a deeper description of some of the leading technologies to date.

Original language	English
Pages (from-to)	64-76
Number of pages	13
Journal	Briefings in Functional Genomics
Volume	17
Issue number	1
DOIs	https://doi.org/10.1093/bfgp/elx019
State	Published - 1 Jan 2018

Keywords

Genomics
RNA sequencing
Single-cell technologies

All Science Journal Classification (ASJC) codes

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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https://doi.org/10.1093/bfgp/elx019

Cite this

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AU - Kalisky, Tomer

AU - Oriel, Sarit

AU - Bar-Lev, Tali Hana

AU - Ben-Haim, Nissim

AU - Trink, Ariel

AU - Wineberg, Yishay

AU - Kanter, Itamar

AU - Gilad, Shlomit

AU - Pyne, Saumyadipta

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AB - In recent years, there has been an effort to develop new technologies formeasuring gene expression and sequence information fromthousands of individual cells. Large data sets that were obtained using these 'single cell' technologies have allowed scientists to address fundamental questions in biomedicine ranging fromstems cells and development to cancer and immunology. Here, we provide a brief review of recent developments in single-cell technology. Our intention is to provide a quick background for newcomers to the field as well as a deeper description of some of the leading technologies to date.

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A brief review of single-cell transcriptomic technologies

Abstract

Keywords

All Science Journal Classification (ASJC) codes

UN SDGs

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