TY - JOUR
T1 - A BID-MTCH2 love story
T2 - Energizing mitochondria until apoptosis do them part?
AU - Gross, Atan
N1 - NA
PY - 2024/2/8
Y1 - 2024/2/8
N2 - Mitochondrial carrier homolog 2 (MTCH2) is currently one of the most enigmatic mitochondrial proteins. MTCH2’s ligand is the pro-apoptotic BID protein, and the love story between these two proteins involves the regulation of diverse cellular processes including apoptosis, energy metabolism, mitochondrial dynamics, and protein insertion into the mitochondrial outer membrane. This review offers an updated progress report of these two proteins and describes our hypotheses regarding their joint mechanism of action.
AB - Mitochondrial carrier homolog 2 (MTCH2) is currently one of the most enigmatic mitochondrial proteins. MTCH2’s ligand is the pro-apoptotic BID protein, and the love story between these two proteins involves the regulation of diverse cellular processes including apoptosis, energy metabolism, mitochondrial dynamics, and protein insertion into the mitochondrial outer membrane. This review offers an updated progress report of these two proteins and describes our hypotheses regarding their joint mechanism of action.
U2 - 10.26124/bec:2024-0001
DO - 10.26124/bec:2024-0001
M3 - مقالة
SN - 2791-4690
VL - 2024
JO - Bioenergetics Communications
JF - Bioenergetics Communications
M1 - 2024.1
ER -