3-Weeks of Prefrontal and Insular Deep TMS Combined With Cue-Induced Craving Significantly Increases Smoking Abstinence: Results From an International, Multi-Site, Randomized, Sham Controlled Trial

Abraham Zangen, Mark George

Research output: Contribution to journalArticlepeer-review

Abstract

Tobacco smoking is the leading cause of preventable death in developed countries. Previous studies in animal models and humans suggest that repeated activation of cue-induced craving networks followed by electromagnetic stimulation of the prefrontal cortex (PFC) can cause lasting reductions in drug craving and consumption. This FDA pivotal double-blind sham-controlled multicenter study was designed to test the effectiveness of deep TMS to PFC and insula to induce smoking cessation.
Original languageAmerican English
Article numberS129
JournalBiological Psychiatry
Volume87
Issue number9 Supp.1
DOIs
StatePublished - 7 May 2020

Keywords

  • Cigarette Smoking
  • Deep TMS
  • Drug Addiction

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