Personal profile
Research interests
Our research is concerned with the application of nanoparticles and nucleic acids with the aim of exploring and exploiting nanoscale advantages in the world of material chemistry, to address significant chemical, biochemical, and technological problems. By approaching nanoscience from a multidisciplinary perspective, integrating biomaterials, inorganic materials, and small molecules via noncovalent and covalent interactions, we can develop new hybrid materials with emergent properties. Our main research objectives are the development of novel strategies and approaches, providing versatile tools to form composite, nano-scaled, precisely-controlled structures and ultra-sensitive DNA machineries. My mentoring and educational objectives are to establish a fascinating and attractive interdisciplinary field that can join students, postdocs, and researchers from different areas of science. I believe that the multidisciplinary emphasis of my research creates an atmosphere of varied and collaborative work that motivates students and promotes independence as they explore new and challenging areas.
Specific Research Topics
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DNA Nanotechnology: Design and applications of novel complex molecular topologies using nucleic acids and their biological consequences.
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Construction and characterization of novel RNA-based self-assemblies for biomedical applications.
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Synthesis of programmable assemblies of colloidal nanoparticles with specific and anisotropic bonding directionality.
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Synthesis, purification, and functionalization of anisotropic nanoparticles for studies relating to plasmonics and biomedical applications.
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Design and development of light-based programmable nucleic acid amplification methods for real-time bioassays using photothermal nanoparticles.
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Collaborations and top research areas from the last five years
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Let There Be Heat: Silica-Coated Gold Nanoparticles as Photothermal Reactors for Chemical Synthesis
Biswas, A., Lemcoff, N. & Weizmann, Y., 6 May 2025, In: Accounts of Chemical Research. 58, 9, p. 1424-1434 11 p.Ben-Gurion University of the Negev
Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular light-to-heat conversion promotes orthogonal synthesis and assembly of metal-organic frameworks
Biswas, A., Lemcoff, N., Shelonchik, O., Baranov, M., Gordon, G., Ben Nun, U. & Weizmann, Y., 1 Dec 2025, In: Nature Communications. 16, 1, 2758.Ben-Gurion University of the Negev
Research output: Contribution to journal › Article › peer-review
Open Access -
Advancing Topoisomerase Research Using DNA Nanotechnology
Yesodi, D., Katz, A. & Weizmann, Y., 1 Jan 2024, (Accepted/In press) In: Small Methods.Ben-Gurion University of the Negev
Research output: Contribution to journal › Article › peer-review
Open Access -
Engineered exosome hybrid copper nanoscale antibiotics facilitate simultaneous self-assembly imaging and elimination of intracellular multidrug-resistant superbugs
Guo, Z., Liu, W., Liu, T., Wang, J., Jiang, H., Liu, X., Weizmann, Y. & Wang, X., 1 Jul 2024, In: Chinese Chemical Letters. 35, 7, 109060.Ben-Gurion University of the Negev
Research output: Contribution to journal › Article › peer-review
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In situ assembly FeS2-tetrathiomolybdate nanosheets for imaging-guided tumor vascular collapse and amplified catalytic therapy
Yin, J., Sun, W., Xiong, H., Xiao, J., Guo, Z., Liu, X., Zhang, B., Jiang, H., Weizmann, Y. & Wang, X., 1 Jun 2024, In: Nano Today. 56, 102244.Ben-Gurion University of the Negev
Research output: Contribution to journal › Article › peer-review