Research output per year
Research output per year
Personal profile
Research interests
The research in the laboratory focuses on signal transduction pathways in macrophages which initiate or down-regulate inflammation. A major interest of the laboratory is to understand how certain endogenous sphingolipids are positively or negatively involved in the inflammatory process, in particular by affecting the activity of Pattern Recognition Receptors (PRRs).
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Collaborations and top research areas from the last five years
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Research output
- 16 Article
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Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones
Rayo, J., Gregor, R., Jacob, N. T., Dandela, R., Dubinsky, L., Yashkin, A., Aranovich, A., Thangaraj, M., Ernst, O., Barash, E., Malitsky, S., Florea, B. I., Krom, B. P., Wiemer, E. A. C., Kickhoefer, V. A., Rome, L. H., Mathison, J. C., Kaufmann, G. F., Overkleeft, H. S., Cravatt, B. F., & 5 others, 23 Mar 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 12, e2012529118.Tel Aviv University, Ben-Gurion University of the Negev
Research output: Contribution to journal › Article › peer-review
Open Access -
Sulfatides are endogenous ligands for the TLR4–MD-2 complex
Su, L., Athamna, M., Wang, Y., Wang, J., Freudenberg, M., Yue, T., Wang, J., Moresco, E. M. Y., He, H., Zor, T. & Beutler, B., 27 Jul 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 30, e2105316118.Research output: Contribution to journal › Article › peer-review
Open Access -
A dual and conflicting role for imiquimod in inflammation: A TLR7 agonist and a cAMP phosphodiesterase inhibitor
Ernst, O., Failayev, H., Athamna, M., He, H., Tsfadia, Y. & Zor, T., 1 Dec 2020, In: Biochemical Pharmacology. 182, 114206.Research output: Contribution to journal › Article › peer-review
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The cAMP Pathway Amplifies Early MyD88-Dependent and Type i Interferon-Independent LPS-Induced Interleukin-10 Expression in Mouse Macrophages
Ernst, O., Glucksam-Galnoy, Y., Athamna, M., Ben-Dror, I., Ben-Arosh, H., Levy-Rimler, G., Fraser, I. D. C. & Zor, T., 1 Jan 2019, In: Mediators of Inflammation. 2019, 3451461.Research output: Contribution to journal › Article › peer-review
Open Access -
3-Aminobenzamide Prevents Concanavalin A-Induced Acute Hepatitis by an Anti-inflammatory and Anti-oxidative Mechanism
Wardi, J., Ernst, O., Lilja, A., Aeed, H., Katz, S., Ben-Nachum, I., Ben-Dror, I., Katz, D., Bernadsky, O., Kandhikonda, R., Avni, Y., Fraser, I. D. C., Weinstain, R., Biro, A. & Zor, T., 1 Dec 2018, In: Digestive Diseases and Sciences. 63, 12, p. 3382-3397 16 p.Research output: Contribution to journal › Article › peer-review