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Dive into the research topics where Rotem Sorek is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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A DNA-gated molecular guard controls bacterial Hailong anti-phage defence
Tan, J. M. J., Melamed, S., Cofsky, J. C., Syangtan, D., Hobbs, S. J., del Mármol, J., Jost, M., Kruse, A. C., Sorek, R. & Kranzusch, P. J., 30 Apr 2025, (Published Online) In: Nature.Research output: Contribution to journal › Article › peer-review
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CARD domains mediate anti-phage defence in bacterial gasdermin systems
Wein, T., Millman, A., Lange, K., Yirmiya, E., Hadary, R., Garb, J., Melamed, S., Amitai, G., Dym, O., Steinruecke, F., Hill, A. B., Kranzusch, P. J. & Sorek, R., 20 Mar 2025, In: Nature. 639, 8055, p. 727-734 8 p.Research output: Contribution to journal › Article › peer-review
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Structure-guided discovery of viral proteins that inhibit host immunity
Yirmiya, E., Hobbs, S. J., Leavitt, A., Osterman, I., Avraham, C., Hochhauser, D., Madhala, B., Skovorodka, M., Tan, J. M. J., Toyoda, H. C., Chebotar, I., Itkin, M., Malitsky, S., Amitai, G., Kranzusch, P. J. & Sorek, R., 20 Mar 2025, In: Cell. 188, 6, p. 1681-1692.e17 30 p.Research output: Contribution to journal › Article › peer-review
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TIR domains produce histidine-ADPR as an immune signal in bacteria
Sabonis, D., Avraham, C., Chang, R. B., Lu, A., Herbst, E., Silanskas, A., Vilutis, D., Leavitt, A., Yirmiya, E., Toyoda, H. C., Ruksenaite, A., Zaremba, M., Osterman, I., Amitai, G., Kranzusch, P. J., Sorek, R. & Tamulaitiene, G., 30 Apr 2025, In: Nature. 642, 8067, p. 467-473 7 p.Research output: Contribution to journal › Article › peer-review
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TIR signaling activates caspase-like immunity in bacteria
Rousset, F., Osterman, I., Scherf, T., Falkovich, A. H., Leavitt, A., Amitai, G., Shir, S., Malitsky, S., Itkin, M., Savidor, A. & Sorek, R., 31 Jan 2025, In: Science. 387, 6733, p. 510-516 7 p.Research output: Contribution to journal › Article › peer-review