Personal profile
Research interests
Mira Barda-Saad is an Associate Professor at the Faculty of Life Sciences of Bar-Ilan University in Israel. She received her PhD in Molecular Immunology (Summa Cum Laude), following a collaborative research at Bar Ilan University and the Weizmann Institute of Science. She performed her first postdoctoral studies at the Weizmann Institute of sciences and the second at the NCI/NIH, Bethesda, MD, USA. She received the Outstanding Fellow Award for Research Excellency (FARE) from the NIH and joined the faculty of Life Sciences at Bar-Ilan University. Her work was recognized by the Israeli Cancer Association as one of the top five studies, and she was awarded the Taubenblatt award for Research Excellence in Biomedicine. Mira Barda-Saad's research focuses on signal transduction mechanisms in immune cells, and specifically on cytoskeletal networks regulating the immune response. Using high-resolution microscopy and cutting edge imaging technologies, she has developed a potential novel therapeutic approach for the primary immunodeficiencies: WAS/XLT. She revealed signaling cascades that lead to actin polymerization and the regulation of immune cell behaviour in health and disease. Prof. Mira Barda-Saad is a member of the editorial boards of Scientific Reports, Nature Publishing group, International Scholarly Research Notices (ISRN), Austin Journal of Clinical Immunology. Since 2012 she is a Committee Member of the Israel Society of Immunology (IIS) and since 2016 she is the president of IIS.
Education/Academic qualification
PhD, Bar-Ilan University
Jan 1994 → Jan 1999
Award Date: 1 Jan 1999
Master
Jan 1988 → Dec 1990
Award Date: 1 Dec 1990
Bachelor, Bar-Ilan University
Jan 1984 → Dec 1987
Award Date: 1 Dec 1987
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Isolation and characterization of primary NK cells and the enrichment of the KIR2DL1+ population
Sabag, B., Puthenveetil, A. & Barda-Saad, M., Jan 2025, The Immunological Synapse - Part C. Thomas, C. & Galluzzi, L. (eds.). Academic Press Inc., p. 201-211 11 p. (Methods in Cell Biology; vol. 193).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Dysfunctional natural killer cells can be reprogrammed to regain anti-tumor activity
Sabag, B., Puthenveetil, A., Levy, M., Joseph, N., Doniger, T., Yaron, O., Karako-Lampert, S., Lazar, I., Awwad, F., Ashkenazi, S. & Barda-Saad, M., 1 Jul 2024, In: EMBO Journal. 43, 13, p. 2552-2581 30 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibition of α4β1 Integrin Activity by Small Tellurium Compounds Regulates PD-L1 Expression and Enhances Antitumor Effects
Chaouat, A., Kalechman, Y., Hay, O., Manoim, J. E., Lantner, T., Niderberg, E., Hauschner, H., Kenigsbuch Sredni, D., Cohen, T., Schlesinger, A., Nadler, R., Barda-Saad, M., Noy, E., Albeck, M., Longo, D. L. & Sredni, B., 12 Aug 2024, In: International Journal of Biological Sciences. 20, 11, p. 4407-4423 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Actin Retrograde Flow Regulated by the Wiskott–Aldrich Syndrome Protein Drives the Natural Killer Cell Response
Sabag, B., Levy, M., Kivelevitz, J., Dashevsky, N., Ben-Shmuel, A., Puthenveetil, A., Awwad, F. & Barda-Saad, M., 2 Aug 2022, In: Cancers. 14, 15, 17 p., 3756.Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibition of SHP-1 activity by PKC-θ regulates NK cell activation threshold and cytotoxicity
Ben-Shmuel, A., Sabag, B., Puthenveetil, A., Biber, G., Levy, M., Jubany, T., Awwad, F., Roy, R. K., Joseph, N., Matalon, O., Kivelevitz, J. & Barda-Saad, M., 8 Mar 2022, In: eLife. 11, 30 p., e73282.Research output: Contribution to journal › Article › peer-review
Open Access