Mickey Kosloff

2023

Gene expression meta-analysis in patients with schizophrenia reveals up-regulation of RGS2 and RGS16 in Brodmann Area 10

Shriebman, Y., Yitzhaky, A., Kosloff, M. & Hertzberg, L., Jan 2023, In: European Journal of Neuroscience. 57, 2, p. 360-372 13 p.

Weizmann Institute of Science, University of Haifa, Tel Aviv University

Research output: Contribution to journal › Article › peer-review

2022

Evolution of homo-oligomerization of methionine S-adenosyltransferases is replete with structure–function constrains

Kleiner, D., Shapiro Tuchman, Z., Shmulevich, F., Shahar, A., Zarivach, R., Kosloff, M. & Bershtein, S., 1 Jul 2022, In: Protein Science. 31, 7, e4352.

Ben-Gurion University of the Negev, University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

2021

A guide to adhesion GPCR research: exploring the structure, function and clinic relevance of adhesion GPCRs using multi-disciplinary approaches

Liebscher, I., Cevheroğlu, O., Hsiao, C. C., Maia, A. F., Schihada, H., Scholz, N., Soave, M., Spiess, K., Trajković, K., Kosloff, M. & Prömel, S., 2021, In: FEBS Journal. 289, 24, p. 1-21 21 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

Ectopic activation of GABA_B receptors inhibits neurogenesis and metamorphosis in the cnidarian Nematostella vectensis

Levy, S., Brekhman, V., Bakhman, A., Malik, A., Sebé-Pedrós, A., Kosloff, M. & Lotan, T., Jan 2021, In: Nature Ecology and Evolution. 5, 1, p. 111-121 11 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Integrative Structural Biology in the Era of Accurate Structure Prediction: The Era of Accurate Structure Prediction

Masrati, G., Landau, M., Ben-Tal, N., Lupas, A., Kosloff, M. & Kosinski, J., 1 Oct 2021, In: Journal of Molecular Biology. 433, 20, p. 1-16 167127.

Tel Aviv University, University of Haifa, Technion - Israel Institute of Technology

Research output: Contribution to journal › Review article › peer-review

Open Access

Residue-level determinants of RGS R4 subfamily GAP activity and specificity towards the G_i subfamily

Asli, A., Higazy-Mreih, S., Avital-Shacham, M. & Kosloff, M., Sep 2021, In: Cellular and Molecular Life Sciences. 78, 17-18, p. 6305-6318 14 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins

Shushan, A. & Kosloff, M., Dec 2021, In: Scientific Reports. 11, 1, p. 1-15 3789.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

2020

The European Research Network on Signal Transduction (ERNEST): Toward a Multidimensional Holistic Understanding of G Protein-Coupled Receptor Signaling

Sommer, M. E., Selent, J., Carlsson, J., De Graaf, C., Gloriam, D. E., Keseru, G. M., Kosloff, M., Mordalski, S., Rizk, A., Rosenkilde, M. M., Sotelo, E., Tiemann, J. K. S., Tobin, A., Vardjan, N., Waldhoer, M. & Kolb, P., 10 Apr 2020, In: ACS Pharmacology and Translational Science. 3, 2, p. 361-370 10 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Author Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells (Scientific Reports, (2018), 8, 1, (653), 10.1038/s41598-017-18851-4)

Qutob, N., Masuho, I., Alon, M., Emmanuel, R., Cohen, I., Di Pizio, A., Madore, J., Elkahloun, A., Ziv, T., Levy, R., Gartner, J. J., Hill, V. K., Lin, J. C., Hevroni, Y., Greenberg, P., Brodezki, A., Rosenberg, S. A., Kosloff, M., Hayward, N. K., Admon, A., & 4 othersNiv, M. Y., Scolyer, R. A., Martemyanov, K. A. & Samuels, Y., 1 Dec 2019, In: Scientific Reports. 9, 1, 4523.

Technion - Israel Institute of Technology, University of Haifa, The Hebrew University of Jerusalem

Research output: Contribution to journal › Comment/debate

Open Access

Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells (vol 8, 653, 2018): RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells (Scientific Reports, (2018), 8, 1, (653), 10.1038/s41598-017-18851-4)

Qutob, N., Masuho, I., Alon, M., Emmanuel, R., Cohen, I., Di Pizio, A., Madore, J., Elkahloun, A., Ziv, T., Levy, R., Gartner, J. J., Hill, V. K., Lin, J. C., Hevroni, Y., Greenberg, P., Brodezki, A., Rosenberg, S. A., Kosloff, M., Hayward, N. K., Admon, A., & 4 othersNiv, M. Y., Scolyer, R. A., Martemyanov, K. A. & Samuels, Y., 9 Mar 2019, In: Scientific Reports. 9, 1, 2 p., 4523.

Weizmann Institute of Science, Technion - Israel Institute of Technology

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Residue-level determinants of angiopoietin-2 interactions with its receptor Tie2

Bakhman, A., Rabinovich, E., Shlamkovich, T., Papo, N. & Kosloff, M., 1 Mar 2019, In: Proteins: Structure, Function and Bioinformatics. 87, 3, p. 185-197 13 p.

Ben-Gurion University of the Negev, University of Haifa

Research output: Contribution to journal › Article › peer-review

RGS6 and RGS7 Discriminate between the Highly Similar Gα_i and Gα_o Proteins Using a Two-Tiered Specificity Strategy

Israeli, R., Asli, A., Avital-Shacham, M. & Kosloff, M., 9 Aug 2019, In: Journal of Molecular Biology. 431, 17, p. 3302-3311 10 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Structural design principles that underlie the multi-specific interactions of Gα _q with dissimilar partners

Navot, S. & Kosloff, M., 1 Dec 2019, In: Scientific Reports. 9, 1, p. 1-10 6898.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Interplay between negative and positive design elements in Gα helical domains of G proteins determines interaction specificity toward RGS2

Kasom, M., Gharra, S., Sadiya, I., Avital-Shacham, M. & Kosloff, M., 25 Jul 2018, In: Biochemical Journal. 475, 14, p. 2293-2304 12 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Neofunctionalization in ligand binding sites of ant olfactory receptors

Saad, R., Cohanim, A. B., Kosloff, M. & Privman, E., 1 Sep 2018, In: Genome Biology and Evolution. 10, 9, p. 2490-2500 11 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

Refinement of the endogenous epitope tagging technology allows the identification of a novel NRAS binding partner in melanoma

Alon, M., Emmanuel, R., Qutob, N., Bakhman, A., Peshti, V., Brodezki, A., Bassan, D., Kosloff, M. & Samuels, Y., 1 Sep 2018, In: Pigment Cell and Melanoma Research. 31, 5, p. 641-648 8 p.

Weizmann Institute of Science, University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells

Qutob, N., Masuho, I., Alon, M., Emmanuel, R., Cohen, I., Di Pizio, A., Madore, J., Elkahloun, A., Ziv, T., Levy, R., Gartner, J. J., Hill, V. K., Lin, J. C., Hevroni, Y., Greenberg, P., Brodezki, A., Rosenberg, S. A., Kosloff, M., Hayward, N. K., Admon, A., & 4 othersNiv, M. Y., Scolyer, R. A., Martemyanov, K. A. & Samuels, Y., 12 Jan 2018, In: Scientific Reports. 8, 1, p. 1-10 10 p., 653.

Weizmann Institute of Science, University of Haifa, Technion - Israel Institute of Technology, The Hebrew University of Jerusalem

Research output: Contribution to journal › Article › peer-review

Open Access

Structural motifs in the RGS RZ subfamily combine to attenuate interactions with Gα subunits

Salem-Mansour, D., Asli, A., Avital-Shacham, M. & Kosloff, M., 18 Sep 2018, In: Biochemical and Biophysical Research Communications. 503, 4, p. 2736-2741 6 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

“Disruptor” residues in the regulator of g protein signaling (RGS) R12 subfamily attenuate the inactivation of g subunits

Asli, A., Sadiya, I., Avital-Shacham, M. & Kosloff, M., 12 Jun 2018, In: Science Signaling. 11, 534, p. 1-10 eaan3677.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Engineering a monomeric variant of macrophage colony-stimulating factor (M-CSF) that antagonizes the c-FMS receptor

Zur, Y., Rosenfeld, L., Bakhman, A., Ilic, S., Hayun, H., Shahar, A., Akabayov, B., Kosloff, M., Levaot, N. & Papo, N., 1 Aug 2017, In: Biochemical Journal. 474, 15, p. 2601-2617 17 p.

Ben-Gurion University of the Negev, University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

Identifying Residues that Determine SCF Molecular-Level Interactions through a Combination of Experimental and In silico Analyses

Rabinovich, E., Heyne, M., Bakhman, A., Kosloff, M., Shifman, J. M. & Papo, N., 6 Jan 2017, In: Journal of Molecular Biology. 429, 1, p. 97-114 18 p.

Ben-Gurion University of the Negev, University of Haifa, The Hebrew University of Jerusalem

Research output: Contribution to journal › Article › peer-review

2013

From protein structure to function via computational tools and approaches

Kolodny, R. & Kosloff, M., Apr 2013, In: Israel Journal of Chemistry. 53, 3-4, p. 147-156 10 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

2012

Compartmentalization and Ca²⁺ buffering are essential for prevention of light-induced retinal degeneration

Weiss, S., Kohn, E., Dadon, D., Katz, B., Peters, M., Lebendiker, M., Kosloff, M., Colley, N. J. & Minke, B., 17 Oct 2012, In: Journal of Neuroscience. 32, 42, p. 14696-14708 13 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

Open Access

Regulator of G-protein signaling-21 (RGS21) is an inhibitor of bitter gustatory signaling found in lingual and airway epithelia

Cohen, S. P., Buckley, B. K., Kosloff, M., Garland, A. L., Bosch, D. E., Cheng Gang, J., Radhakrishna, H., Brown, M. D., Willard, F. S., Arshavsky, V. Y., Tarran, R., Siderovski, D. P. & Kimple, A. J., 7 Dec 2012, In: Journal of Biological Chemistry. 287, 50, p. 41706-41719 14 p.

University of Haifa

Research output: Contribution to journal › Article › peer-review

2011

Cooperative phosphoinositide and peptide binding by PSD-95/discs large/ZO-1 (PDZ) domain of polychaetoid, Drosophila zonulin

Ivarsson, Y., Wawrzyniak, A. M., Wuytens, G., Kosloff, M., Vermeiren, E., Raport, M. & Zimmermann, P., 30 Dec 2011, In: Journal of Biological Chemistry. 286, 52, p. 44669-44678 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions

Kosloff, M., Travis, A. M., Bosch, D. E., Siderovski, D. P. & Arshavsky, V. Y., Jul 2011, In: Nature Structural and Molecular Biology. 18, 7, p. 846-853 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Kosloff Mickey

Research output

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