Sharon Michal

Research output

Research output per year 2007 2013 2014 2015 2017 2018 2019 2020 2021 2022 2025

• 65 Article
• 11 Review article
• 3 Chapter
• 3 Editorial
• 4 More
  • 2 Letter
  • 1 Conference article
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2025

  Molecular insights into the unique properties of the blood-circulating proteasome

  Leushkin, Y., Morgenstern, D., Ben-Dor, S., Haffner-Krausz, R., Zittlau, K., Ben-Nissan, G. & Sharon, M., Jan 2025, In: Journal of Extracellular Biology. 4, 1, e70034.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Tracking proteasome degradation: A cross-organ analysis via intact degradomics mass spectrometry

  Zittlau, K. I., Zachor-Movshovitz, D., Leushkin, Y., Schimmel Brener, R., Morgenstern, D., Ben-Nissan, G. & Sharon, M., 25 Feb 2025, In: Proceedings of the National Academy of Sciences - PNAS. 122, 8, e2419607122.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2024

  Controlling the incorporation of fluorinated amino acids in human cells and its structural impact

  Costantino, A., Pham, L. B. T., Barbieri, L., Calderone, V., Ben-Nissan, G., Sharon, M., Banci, L. & Luchinat, E., Mar 2024, In: Protein Science. 33, 3, e4910.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  • Aromatic Amino Acids 100%
  • Aromatic Amino Acid 81%
  • Amino Acids 49%
  • Acid 24%
  • X-Rays 18%

• Systematic identification of 20S proteasome substrates

  Pepelnjak, M., Rogawski, R., Arkind, G., Leushkin, Y., Fainer, I., Ben-Nissan, G., Picotti, P. & Sharon, M., 2 Apr 2024, In: Molecular Systems Biology. 20, 4, p. 403-427 25 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex 100%
  • proteasome endopeptidase complex 59%
  • Substrate 59%
  • Protein 38%
  • Substrates 36%
• 2023

  Allosteric regulation of the 20S proteasome by the Catalytic Core Regulators (CCRs) family

  Deshmukh, F. K., Ben-Nissan, G., Olshina, M. A., Füzesi-Levi, M. G., Polkinghorn, C., Arkind, G., Leushkin, Y., Fainer, I., Fleishman, S. J., Tawfik, D. & Sharon, M., 30 May 2023, In: Nature Communications. 14, 1, 3126.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Allosteric Regulation 100%
  • regulators 85%
  • Proteasome Endopeptidase Complex 70%
  • Catalytic Domain 60%
  • proteins 53%

• C-terminal domain dimerization in yeast Hsp90 is moderately modulated by the other domains

  Oranges, M., Giannoulis, A., Vanyushkina, A., Sirkis, Y. F., Dalaloyan, A., Unger, T., Su, X. C., Sharon, M. & Goldfarb, D., 10 Dec 2023, (Published Online) In: Biophysical Journal.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  • HSP90 Heat-Shock Proteins 100%
  • Fungal Proteins 94%
  • Dimerization 85%
  • Electrons 40%
  • Protein Multimerization 19%

• The C-terminal tail of CSNAP attenuates the CSN complex

  Füzesi-Levi, M. G., Ben-Nissan, G., Listov, D., Fridmann Sirkis, Y., Hayouka, Z., Fleishman, S. & Sharon, M., 1 Oct 2023, In: Life Science Alliance. 6, 10, 12 p., e202201634.

  Weizmann Institute of Science, The Hebrew University of Jerusalem

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • COP9 Signalosome Complex 100%
  • constitutive photomorphogenesis 9 signalosome 99%
  • Cullin Proteins 54%
  • tail 49%
  • family 42%
• 2022

  A counter-enzyme complex regulates glutamate metabolism in Bacillus subtilis

  Jayaraman, V., Lee, D. J., Elad, N., Vimer, S., Sharon, M., Fraser, J. S. & Tawfik, D. S., Feb 2022, In: Nature Chemical Biology. 18, 2, p. 161-170 10 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bacillus subtilis 100%
  • Glutamic Acid 80%
  • Enzymes 50%
  • Glutamate Synthase 23%
  • Growth 19%

• A counter-enzyme complex regulates glutamate metabolism in Bacillus subtilis

  Jayaraman, V., Lee, D. J., Elad, N., Vimer, S., Sharon, M., Fraser, J. S. & Tawfik, D. S., 1 Feb 2022, In: Nature Chemical Biology. 18, 2, p. 161-170 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Biology of the Extracellular Proteasome

  Ben-Nissan, G., Katzir, N., Füzesi-Levi, M. G. & Sharon, M., May 2022, In: Biomolecules (Basel, Switzerland). 12, 5, 22 p., 619.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex 100%
  • Biological Role 59%
  • Protein 39%
  • Plasma 29%
  • Body Fluids 26%

• Influence of Asp Isomerization on Trypsin and Trypsin-like Proteolysis

  Silzel, J. W., Ben-Nissan, G., Tang, J., Sharon, M. & Julian, R. R., 8 Nov 2022, In: Analytical chemistry (Washington). 94, 44, p. 15288-15296 9 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteolysis 100%
  • Isomerization 77%
  • Protein Hydrolysis 57%
  • Trypsin 50%
  • Proteins 48%

• Surface-Induced Dissociation for Protein ComplexProtein complexes Characterization

  Harvey, S. R., Ben-Nissan, G., Sharon, M. & Wysocki, V. H., 4 Jun 2022, Proteoform Identification. p. 211-237 27 p. (Methods in Molecular Biology; vol. 2500).

  Weizmann Institute of Science

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • protein 100%
  • mass spectrometry 78%
  • connectivity 39%
  • resource 25%
  • stoichiometry 25%

• Targeted protein degradation: from small molecules to complex organelles—a Keystone Symposia report

  Cable, J., Weber-Ban, E., Clausen, T., Walters, K. J., Sharon, M., Finley, D. J., Gu, Y., Hanna, J., Feng, Y., Martens, S., Simonsen, A., Hansen, M., Zhang, H., Goodwin, J. M., Reggio, A., Chang, C., Ge, L., Schulman, B. A., Deshaies, R. J., Dikic, I., & 12 othersHarper, J. W., Wertz, I. E., Thomä, N. H., Słabicki, M., Frydman, J., Jakob, U., David, D. C., Bennett, E. J., Bertozzi, C. R., Sardana, R., Eapen, V. V. & Carra, S., Apr 2022, In: Annals of the New York Academy of Sciences. 1510, 1, p. 79-99 21 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Keystone 100%
  • Protein 91%
  • Degradation 77%
  • Proteolysis 71%
  • Molecules 70%
• 2021

  20S proteasomes secreted by the malaria parasite promote its growth

  Dekel, E., Yaffe, D., Rosenhek-Goldian, I., Ben-Nissan, G., Ofir-Birin, Y., Morandi, M. I., Ziv, T., Sisquella, X., Pimentel, M. A., Nebl, T., Kapp, E., Ohana Daniel, Y., Karam, P. A., Alfandari, D., Rotkopf, R., Malihi, S., Temin, T. B., Mullick, D., Revach, O. Y., Rudik, A., & 11 othersGov, N. S., Azuri, I., Porat, Z., Bergamaschi, G., Sorkin, R., Wuite, G. J. L., Avinoam, O., Carvalho, T. G., Cohen, S. R., Sharon, M. & Regev-Rudzki, N., 1 Dec 2021, In: Nature Communications. 12, 1, p. 1172 19 p., 1172.

  Weizmann Institute of Science, Tel Aviv University, Technion - Israel Institute of Technology

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • parasites 100%
  • Proteasome Endopeptidase Complex 72%
  • Extracellular Vesicles 65%
  • Malaria 63%
  • erythrocytes 60%

• Albumin-edta-vanadium is a powerful anti-proliferative agent, following entrance into glioma cells via caveolae-mediated endocytosis

  Cooper, I., Ravid, O., Rand, D., Atrakchi, D., Shemesh, C., Bresler, Y., Ben-Nissan, G., Sharon, M., Fridkin, M. & Shechter, Y., 25 Sep 2021, In: Pharmaceutics. 13, 10, 1557.

  Weizmann Institute of Science, Tel Aviv University

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vanadium 100%
  • Caveolae 89%
  • Endocytosis 69%
  • Antiproliferative 69%
  • Glioma 64%

• Beyond cells: The extracellular circulating 20S proteasomes

  Dwivedi, V., Yaniv, K. & Sharon, M., 1 Mar 2021, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1867, 3, 9 p., 166041.

  Weizmann Institute of Science

  Research output: Contribution to journal › Review article › peer-review

  • Proteasome Endopeptidase Complex 100%
  • Skin Neoplasms 14%
  • Sepsis 11%
  • Survival Rate 10%
  • Clinical Studies 9%

• Cell communication and protein degradation: All in one parasitic package

  Sharon, M. & Regev-Rudzki, N., Jul 2021, In: Journal of Extracellular Vesicles. 10, 9, e12116.

  Weizmann Institute of Science

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

• Characterizing Endogenous Protein Complexes with Biological Mass Spectrometry

  Rogawski, R. & Sharon, M., 18 Aug 2021, In: Chemical Reviews. 122, 8, p. 7386-7414 29 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Mass Spectrometry 100%
  • Protein 62%
  • Heterogeneity 27%
  • Reaction Yield 24%
  • Reaction Stoichiometry 24%

• Direct-MS analysis of antibody-antigen complexes

  Vimer, S., Ben-Nissan, G., Marty, M., Fleishman, S. J. & Sharon, M., Nov 2021, In: Proteomics. 21, 21-22, 11 p., 2000300.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antigen-Antibody Complex 100%
  • Antigen 80%
  • Purification 65%
  • Antigens 61%
  • Antibodies 53%

• Helicase-like functions in phosphate loop containing beta-alpha polypeptides

  Vyas, P., Trofimyuk, O., Longo, L. M., Deshmukh, F. K., Sharon, M. & Tawfik, D. S., 12 Apr 2021, In: Proceedings of the National Academy of Sciences - PNAS. 118, 16, e2016131118.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • AAA Domain 100%
  • Phosphates 60%
  • Peptides 44%
  • triphosphoric acid 35%
  • AAA Proteins 32%

• Intracellular Protein–Drug Interactions Probed by Direct Mass Spectrometry of Cell Lysates

  Rogawski, R., Rogel, A., Bloch, I., Gal, M., Horovitz, A., London, N. & Sharon, M., 1 Sep 2021, In: Angewandte Chemie - International Edition. 60, 36, p. 19637-19642 6 p.

  Weizmann Institute of Science, Tel Aviv University

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mass spectrometry 100%
  • Mass Spectrometry 52%
  • Drug 41%
  • Proteins 35%
  • Lead compounds 33%

• Introducing …: Michal Sharon

  Sharon, M., 1 Sep 2021, In: Angewandte Chemie (International Edition in English). 60, 36, 1 p., anie.202108629.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article

  Open Access

  • Proteasome Endopeptidase Complex 100%
  • Molecules 50%
  • Molecule 17%

• Quinone Methide‐Based Organophosphate Hydrolases Inhibitors: Trans Proximity Labelers versus Cis Labeling Activity‐Based Probes

  Dubovetskyi, A., Cherukuri, K. P., Ashani, Y., Meshcheriakova, A., Reuveny, E., Ben‐Nissan, G., Sharon, M., Fumagalli, L. & Tawfik, D. S., 2 Mar 2021, In: Chembiochem : a European journal of chemical biology. 22, 5, p. 894-903 10 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  • phosphorylphosphatase 100%
  • quinone methide 89%
  • Hydrolase Inhibitor 77%
  • quinone 59%
  • Quinone 46%
• 2020

  Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry

  Vimer, S., Ben-Nissan, G., Morgenstern, D., Kumar-Deshmukh, F., Polkinghorn, C., Quintyn, R. S., Vasil'ev, Y. V., Beckman, J. S., Elad, N., Wysocki, V. H. & Sharon, M., 22 Apr 2020, In: ACS Central Science. 6, 4, p. 573-588 16 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex 100%
  • Mass spectrometry 65%
  • Structural analysis 52%
  • Proteins 47%
  • Rats 34%

• Computational Strategies and Challenges for Using Native Ion Mobility Mass Spectrometry in Biophysics and Structural Biology

  Allison, T. M., Barran, P., Cianferani, S., Degiacomi, M. T., Gabelica, V., Grandori, R., Marklund, E. G., Menneteau, T., Migas, L. G., Politis, A., Sharon, M., Sobott, F., Thalassinos, K. & Benesch, J. L. P., 18 Aug 2020, In: Analytical Chemistry. 92, 16, p. 10872-10880 9 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  • Biophysics 100%
  • biophysics 91%
  • Mass spectrometry 80%
  • Ions 57%
  • mass spectrometry 53%

• CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligases

  Fuzesi-Levi, M. G., Fainer, I., Enchev, R. I., Ben-Nissan, G., Levin, Y., Kupervaser, M., Salame, T. M., Nevo, R., Peter, M. & Sharon, M., Mar 2020, In: Cell Death and Differentiation. 27, 3, p. 984-998 15 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  • COP9 Signalosome Complex 100%
  • Cullin Proteins 87%
  • Proteostasis 78%
  • Ligases 65%
  • Ubiquitin 59%

• Direct characterization of overproduced proteins by native mass spectrometry

  Vimer, S., Ben-Nissan, G. & Sharon, M., Feb 2020, In: NATURE PROTOCOLS. 15, 2, p. 236-265 30 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mass Spectrometry 100%
  • Glycosylation 57%
  • Recombinant Proteins 54%
  • Protein 45%
  • Proteins 40%

• Erratum: Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces (PLoS Computational Biology(2019)15: 8(e1007207)Doi: 10.1371/journal.pcbi.1007207)

  Warszawski, S., Katz, A. B., Lipsh, R., Khmelnitsky, L., Nissan, G. B., Javitt, G., Dym, O., Unger, T., Knop, O., Albeck, S., Diskin, R., Fass, D., Sharon, M. & Fleishman, S. J., 21 Oct 2020, In: PLoS Computational Biology. 16, 10, 1 p., e1008382.

  Weizmann Institute of Science, Bar-Ilan University

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • antibody affinity 100%
  • Antibody 96%
  • Computational Biology 91%
  • Antibodies 91%
  • Antibody Affinity 89%

• Insight into the Autosomal-Dominant Inheritance Pattern of SOD1-Associated ALS from Native Mass Spectrometry

  Cveticanin, J., Mondal, T., Meiering, E. M., Sharon, M. & Horovitz, A., 20 Nov 2020, In: Journal of Molecular Biology. 432, 23, p. 5995-6002 8 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  • Inheritance Patterns 100%
  • Amyotrophic Lateral Sclerosis 83%
  • Mass Spectrometry 70%
  • Amyotrophic lateral sclerosis 1 34%
  • Superoxide Dismutase 23%

• Mass spectrometry analysis of intact proteins from crude samples

  Vimer, S., Ben-Nissan, G. & Sharon, M., 6 Oct 2020, In: Analytical Chemistry. 92, 19, p. 12741-12749 9 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mass spectrometry 100%
  • Proteins 71%
  • mass spectrometry 66%
  • protein 56%
  • Electrospray ionization 49%

• Regulation of the 20S Proteasome by a Novel Family of Inhibitory Proteins

  Olshina, M. A., Arkind, G., Deshmukh, F. K., Fainer, I., Taranavsky, M., Hayat, D., Ben-Dor, S., Ben-Nissan, G. & Sharon, M., Mar 2020, In: Antioxidants & Redox Signaling. 32, 9, p. 636-655 20 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex 100%
  • Oxidative Stress 56%
  • Protein 39%
  • Proteins 35%
  • Catalytic Domain 24%

• Software Requirements for the Analysis and Interpretation of Native Ion Mobility Mass Spectrometry Data

  Allison, T. M., Barran, P., Benesch, J. L. P., Cianferani, S., Degiacomi, M. T., Gabelica, V., Grandori, R., Marklund, E. G., Menneteau, T., Migas, L. G., Politis, A., Sharon, M., Sobott, F. & Thalassinos, K., 18 Aug 2020, In: Analytical Chemistry. 92, 16, p. 10881-10890 10 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Review article › peer-review

  • Mass spectrometry 100%
  • Instrumentation 75%
  • Ions 71%
  • mass spectrometry 66%
  • Mass Spectrometry 52%

• The COVID-19 MS Coalition-accelerating diagnostics, prognostics, and treatment

  6 Jun 2020, In: Lancet. 395, 10239, p. 1761-1762 2 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Letter › peer-review

  Open Access
• 2019

  Dissecting the molecular effects of cigarette smoke on proteasome function

  Kammerl, I. E., Caniard, A., Merl-Pham, J., Ben-Nissan, G., Mayr, C. H., Mossina, A., Geerlof, A., Eickelberg, O., Hauck, S. M., Sharon, M. & Meiners, S., 20 Feb 2019, In: Journal of Proteomics. 193, p. 1-9 9 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  • Smoke 100%
  • Proteasome Endopeptidase Complex 91%
  • Tobacco Products 82%
  • ATP dependent 26S protease 46%
  • Lung 29%

• Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces

  Warszawski, S., Katz, A. B., Lipsh, R., Khmelnitsky, L., Ben Nissan, G., Javitt, G., Dym, O., Unger, T., Knop, O., Albeck, S., Diskin, R., Fass, D., Sharon, M. & Fleishman, S. J., 23 Aug 2019, In: PLoS Computational Biology. 15, 8, 24 p., e1007207.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • antibody affinity 100%
  • Antibody 96%
  • Antibodies 91%
  • Antibody Affinity 89%
  • Affine transformation 80%

• Structural mass spectrometry approaches to study the 20S proteasome

  Ben-Nissan, G., Vimer, S., Tarnavsky, M. & Sharon, M., 1 Feb 2019, (Published Online) Ubiquitin-dependent Protein Degradation. Hochstrasser, M. (ed.). Academic Press Inc., Vol. 619. p. 179-223 45 p. (Methods in Enzymology; vol. 619).

  Weizmann Institute of Science

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Proteasome Endopeptidase Complex 100%
  • Mass Spectrometry 86%
  • Heterogeneity 58%
  • Archaea 29%
  • Reaction Stoichiometry 25%

• The Contribution of the 20S Proteasome to Proteostasis

  Deshmukh, F. K., Yaffe, D., Olshina, M. A., Ben-Nissan, G. & Sharon, M., 16 May 2019, In: Biomolecules. 9, 5, 16 p., 190.

  Weizmann Institute of Science

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Proteostasis 100%
  • Proteasome Endopeptidase Complex 79%
  • Oxidative Stress 37%
  • ATP dependent 26S protease 35%
  • Communication 34%

• The interdimeric interface controls function and stability of Ureaplasma urealiticum methionine S-adenosyltransferase

  Kleiner, D., Shmulevich, F., Zarivach, R., Sharon, M., Ben-Nissan, G., Bershtein, S. & Sharon, M., 6 Dec 2019, In: Journal of Molecular Biology. 431, 24, p. 4796-4816 21 p.

  Ben-Gurion University of the Negev, Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Methionine Adenosyltransferase 100%
  • Ureaplasma 93%
  • Catalytic Domain 55%
  • S-Adenosylmethionine 53%
• 2018

  Conformational states during vinculin unlocking differentially regulate focal adhesion properties

  Chorev, D. S., Volberg, T., Livne, A., Eisenstein, M., Martins, B., Kam, Z., Jockusch, B. M., Medalia, O., Sharon, M. & Geiger, B., 1 Dec 2018, In: Scientific Reports. 8, 1, 14 p., 2693.

  Ben-Gurion University of the Negev, Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vinculin 100%
  • Focal Adhesions 86%
  • Integrins 23%
  • Talin 17%
  • Mechanical Stress 14%

• Estimating Interprotein Pairwise Interaction Energies in Cell Lysates from a Single Native Mass Spectrum

  Cveticanin, J., Netzer, R., Arkind, G., Fleishman, S. J., Horovitz, A. & Sharon, M., 4 Sep 2018, In: Analytical Chemistry. 90, 17, p. 10090-10094 5 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hydrogen bonds 100%
  • Mass spectrometry 93%
  • Escherichia coli 92%
  • Isotherms 87%
  • Amino acids 86%

• Functional regulation of proteins by 20S proteasome proteolytic processing

  Olshina, M. A., Ben-Nissan, G. & Sharon, M., 9 Feb 2018, In: Cell Cycle. 17, 4, p. 393-394 2 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Rapid characterization of secreted recombinant proteins by native mass spectrometry

  Ben-Nissan, G., Vimer, S., Warszawski, S., Katz, A., Yona, M., Unger, T., Peleg, Y., Morgenstern, D., Cohen-Dvashi, H., Diskin, R., Fleishman, S. J. & Sharon, M., 3 Dec 2018, In: Communications Biology. 1, 1, 12 p., 213.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Recombinant Proteins 100%
  • recombinant proteins 99%
  • Mass Spectrometry 91%
  • mass spectrometry 85%
  • Protein 42%

• Simple yet functional phosphate-loop proteins

  Romero Romero, M. L., Yang, F., Lin, Y-R., Toth-Petroczy, A., Berezovsky, I. N., Goncearenco, A., Yang, W., Wellner, A., Kumar-Deshmukh, F., Sharon, M., Baker, D., Varani, G. & Tawfik, D. S., 18 Dec 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. E11943-E11950 8 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phosphates 100%
  • Polynucleotides 51%
  • Proteins 42%
  • Nucleoside-Triphosphatase 36%
  • Walkers 33%

• The application of ion-mobility mass spectrometry for structure/function investigation of protein complexes

  Ben-Nissan, G. & Sharon, M., Feb 2018, In: Current Opinion in Chemical Biology. 42, p. 25-33 9 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Ion Mobility Spectrometry 100%
  • Mass Spectrometry 50%
  • Protein 23%
  • Proteins 20%
  • Application 17%

• Time-Resolved NMR Analysis of Proteolytic α-Synuclein Processing in vitro and in cellulo

  Limatola, A., Eichmann, C., Ben-Nissan, G., Sharon, M., Binolfi, A. & Selenko, P., Nov 2018, In: Proteomics. 18, 21-22, 13 p., 1800056.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Synucleins 100%
  • Protein Hydrolysis 71%
  • Mammalian Cell 34%
  • Oxidative Stress 32%
  • In Vitro Techniques 28%
• 2017

  Concentration-based self-assembly of phycocyanin

  Eisenberg, I., Harris, D., Levi-Kalisman, Y., Yochelis, S., Shemesh, A., Ben-Nissan, G., Sharon, M., Raviv, U., Adir, N., Keren, N. & Paltiel, Y., 1 Oct 2017, In: Photosynthesis Research. 134, 1, p. 39-49 11 p.

  Technion - Israel Institute of Technology, The Hebrew University of Jerusalem

  Research output: Contribution to journal › Article › peer-review

  • Phycocyanin 100%
  • Cope Reaction 78%
  • phycocyanin 78%
  • Oligomerization 61%
  • Trimer 58%

• Measuring inter-protein pairwise interaction energies from a single native mass spectrum by double-mutant cycle analysis

  Sokolovski, M., Cveticanin, J., Hayoun, D., Korobko, I., Sharon, M. & Horovitz, A., 1 Dec 2017, In: Nature Communications. 8, 1, 212.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Native Mass Spectrometry of Recombinant Proteins from Crude Cell Lysates

  Gan, J., Ben-Nissan, G., Arkind, G., Tarnavsky, M., Trudeau, D., Garcia, L. N., Tawfik, D. & Sharon, M., 18 Apr 2017, In: Analytical Chemistry. 89, 8, p. 4398-4404 7 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Recombinant proteins 100%
  • Mass spectrometry 74%
  • Purification 65%
  • purification 54%
  • Proteins 52%

• Post-translational regulation of p53 function through 20S proteasome-mediated cleavage

  Solomon, H., Brauning, B., Fainer, I., Ben-Nissan, G., Rabani, S., Goldfinger, N., Moscovitz, O., Shakked, Z., Rotter, V. & Sharon, M., Dec 2017, In: Cell Death and Differentiation. 24, p. 2187-2198 12 p.

  Weizmann Institute of Science

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex 100%
  • Protein Isoforms 77%
  • Proteins 26%
  • Transcriptional Activation 21%
  • Transcription Factors 18%

• Protein and peptide cross sections and mass spectra in an electrostatic ion beam trap

  Fradkin, Z., Strasser, D., Heber, O., Rappaport, M. L., Sharon, M., Thomson, B. A., Rahinov, I., Toker, Y. & Zajfman, D., 12 May 2017, In: Journal of Instrumentation. 12, 5, P05008.

  Weizmann Institute of Science, The Hebrew University of Jerusalem, Open University of Israel, Bar-Ilan University

  Research output: Contribution to journal › Article › peer-review

  • Peptides 100%
  • Ion beams 99%
  • Trap 88%
  • Electrostatics 82%
  • peptides 78%