Research output per year
Research output per year
Personal profile
Research interests
Our research group investigates the underlying mechanisms that drive neurological disorders (from autoimmune and degenerative diseases to cancer) and translates that knowledge into meaningful medical advances.
In particular, we study how the interactions between the immune system, brain cells, and the unique metabolic landscape of the central nervous system control the progression of diseases such as Multiple sclerosis, Parkinson’s disease, and brain tumors.
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Collaborations and top research areas from the last five years
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Research output
- 16 Article
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Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity
Perelroizen, R., Philosof, B., Budick-Harmelin, N., Chernobylsky, T., Ron, A., Katzir, R., Shimon, D., Tessler, A., Adir, O., Gaoni-Yogev, A., Meyer, T., Krivitsky, A., Shidlovsky, N., Madi, A., Ruppin, E. & Mayo, L., 1 Sep 2022, In: Brain. 145, 9, p. 3288-3307 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity
Meyer, T., Shimon, D., Youssef, S., Yankovitz, G., Tessler, A., Chernobylsky, T., Gaoni-Yogev, A., Perelroizen, R., Budick-Harmelin, N., Steinman, L. & Mayo, L., 30 Aug 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 35, e2211310119.Research output: Contribution to journal › Article › peer-review
Open Access -
Blood glutamate scavengers increase pro-apoptotic signaling and reduce metastatic melanoma growth in-vivo
Goldshmit, Y., Perelroizen, R., Yakovchuk, A., Banyas, E., Mayo, L., David, S., Benbenishty, A., Blinder, P., Shalom, M. & Ruban, A., 1 Dec 2021, In: Scientific Reports. 11, 1, 14644.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell composition analysis of bulk genomics using single-cell data
Frishberg, A., Peshes-Yaloz, N., Cohn, O., Rosentul, D., Steuerman, Y., Valadarsky, L., Yankovitz, G., Mandelboim, M., Iraqi, F. A., Amit, I., Mayo, L., Bacharach, E. & Gat-Viks, I., 1 Apr 2019, In: Nature Methods. 16, 4, p. 327-332 6 p.Tel Aviv University, Weizmann Institute of Science
Research output: Contribution to journal › Article › peer-review
Open Access -
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39
Takenaka, M. C., Gabriely, G., Rothhammer, V., Mascanfroni, I. D., Wheeler, M. A., Chao, C. C., Gutiérrez-Vázquez, C., Kenison, J., Tjon, E. C., Barroso, A., Vandeventer, T., de Lima, K. A., Rothweiler, S., Mayo, L., Ghannam, S., Zandee, S., Healy, L., Sherr, D., Farez, M. F., Pratt, A., & 7 others, 1 May 2019, In: Nature Neuroscience. 22, 5, p. 729-740 12 p.Research output: Contribution to journal › Article › peer-review
Open Access