Personal profile

Research interests

I Head the Musculoskeletal Genetics Lab at Bar-Ilan's Medical School.

My overall expertise is in the field of inter-personal variability of musculoskeletal (MSK) aging. My research focuses on locating genes underlying the genetic variation of complex MSK traits. Osteoporotic fractures of the hip and spine are an important and widespread health problem. There is a bone-muscle cross-talk in norm and pathology. I was the first to summarize both theoretical and empirical evidence that the MSK system develops, functions, and ages as a whole, and that these processes are governed by genes. We use functional studies (in-vivo and in-vitro) to validate the pleiotropic genes discovered by genome-wide association studies, Using sophisticated MSK imaging techniques, we compare newly-measurable phenotypes obtained in both humans (HR-pQCT) and animal models (microCT). My continuous efforts are aimed on educating graduate and medical students in comparative anatomy, for better understanding and implementing preclinical research findings into human clinical trials for fracture treatment and prevention.

Fields of Interest

Genetic epidemiology of musculoskeletal diseases.

Genetics of Musculoskeletal Disease

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD, Tel Aviv University

Oct 1996Mar 2000

Award Date: 1 Mar 2000

Master, Tel Aviv University

Oct 1991Jul 1996

Award Date: 30 Jul 1996

Bachelor

Sep 1985Jan 1991

Award Date: 30 Jan 1991

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