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Chaya Brodie

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Brodie Chaya

Bar-Ilan University

20112026

Research activity per year

Personal profile

Research interests

  1. Studying the role of protein kinase C in the regulation of cellular growth, differentiation and apoptosis.
  2. Studying the molecular mechanisms underlying the development of brain tumors: Exploring signal transduction pathways involved in glial cell transformation and identification of novel proteins and genes expressed in brain tumors;  development of in vivo and in vitro models of brain tumors; development of novel diagnostic and therapeutic approaches for brain tumors; studying the role of stem cells in the development of brain tumors and their use as a vehicle in gene therapy.
  3. The bi-directional interaction between the nervous and immune systems and the role of this interaction in the function of neuronal and glial cells during physiological and pathological conditions.

Education/Academic qualification

PhD, Bar-Ilan University

… → Jan 1983

Award Date: 1 Jan 1983

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  • A framework for using DNA methylation-based modelling for the clinical management of cranial meningioma

    Landry, A. P., Wang, J. Z., Patil, V., Ajisebutu, A., Gui, C., Yefet, L. S., Ellenbogen, Y., Liu, J., Mamatjan, Y., Wei, Q., Singh, O., Mansouri, S., Ehret, F., Capper, D., Cohen-Gadol, A. A., Tabatabai, G., Tatagiba, M., Behling, F., Barnholtz-Sloan, J. S. & Sloan, A. E. & 139 others, Chambless, L. B., Mansouri, A., Makarenko, S., Yip, S., Tsang, D. S., Gao, A., Aldape, K., Nassiri, F., Zadeh, G., Santarius, T., Selman, W., Couce, M., Sloan, A. E., Brastianos, P. K., Shih, H. A., Linda Bi, W., Huang, R. Y., Wen, P. Y., Walbert, T., Lee, I., Felicella, M., Brodie, C., Malta, T., Castro, A. V. C., Noushmehr, H., Snyder, J., Dimeco, F., Saladino, A., Pollo, B., Schichor, C., Tonn, J. C., Kaufmann, T. J., Lachance, D., Giannini, C., Galanis, E., Raghunathan, A., Hanemann, C. O., Au, K., Goldbrunner, R., Galldiks, N., Timmer, M., Ole Schimdt, N., Herold-Mende, C., Sahm, F., Jungk, C., Jungwirth, G., Von Deimling, A., Jenkinson, M. D., Millward, C. P., Islim, A. I., Drummond, K., Morokoff, A., Tabatabai, G., Behling, F., Renovanz, M., Tatagiba, M., Santacroce, A., La Fougere, C., Schittenhelm, J., Raleigh, D. R., Perry, A., Butowski, N., Westphal, M., Lamszus, K., Ricklefs, F., Mawrin, C., Horbinski, C. M., Ng, H. K., Snuderl, M., Kurz, S., Sulman, E. P., Zada, G., Cohen-Gadol, A., Yip, S., Makarenko, S., Zherebitskiy, V., Hnenny, L., Dunn, I. F., Moliterno, J., McDermott, M. W., Vogelbaum, M., Javadpour, M., Fountain, D., Mathiesen, T. I., Aldape, K., Barnholtz-Sloan, J., Pathmanaban, O., Boutros, P. C., Alkividias, T., Fountas, K. N., Walsh, K. M., Short, S. C., Carvalho, B., Maas, S. L. N., Bos, E. M., Dincer, A., Kurz, S., Passlack, P., Deng, M., Ehret, F., Mehta, M. P., Odia, Y., Everson, R., Balogun, J. A., Lopez, C., Calabrese, E., Karschnia, P., Teske, N., Fariselli, L., Greve, T., Arvaniti, C., Benjamin, C., Ivan, M., Jackson, C., Jeyaretna, S., Scartoni, D., Amelio, D., Palmer, J., Ivanidze, J., Ostrom, Q., Trung Kien, D., Youngblood, M., Millareschavez, M., Althgafi, M., Emerson, S., Weller, M., Lerhun, E., Martínez-Pérez, R., Smee, R., Mukherjee, R., Cervio, A., Turner, C., Muirhead, W., Molina, E. S., Julius, V., Chen, J., Karmur, B., Mrugala, M. & Neth, B., 1 Feb 2026, In: Neuro-Oncology. 28, 2, p. 430-439 10 p.

    Bar-Ilan University

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Ouabain – a double-edged sword in tumor development and progression? a review of half a century

    Weidemann, H., Sarsour, A. D. & Brodie, C., 2025, In: Frontiers in Physiology. 16, 1685871.

    Bar-Ilan University

    Research output: Contribution to journal › Review article › peer-review

    Open Access

  • Preanalytical variables and analytes in liquid biopsy approach for brain tumors: A comprehensive review and recommendations from the RANO Group and the Brain Liquid Biopsy Consortium

    Bettegowda, C., Noushmehr, H., Affinito, A., Ahluwalia, M. S., Ansorge, O., Ayasoufi, K., Bagley, S., Barnholtz-Sloan, J., Best, M., Brandsma, D., Brodie, C., Brüning-Richardson, A., Castro, A. V., Chang, S. M., Condorelli, G., Daher, A., Datta, V., De Groot, J., French, P. & Galanis, E. & 29 others, Golebiewska, A., Hamerlik, P., Hanemann, C. O., Holdhoff, M., Huse, J., Khasraw, M., Leblang, S., Melin, B., Mouliere, F., O'Leary, C., Rak, J., Ray, A., Robinson, S., Rominiyi, O., Roncaroli, F., Rudà, R., Seoane, J., Sol, N., Van Den Bent, M. J., Vogelbaum, M. A., Walbert, T., Watts, C., Weiss, T., Weller, M., Wen, P. Y., Wykes, V., Yip, S., Short, S. C. & Soffietti, R., 1 Oct 2025, In: Neuro-Oncology. 27, 10, p. 2496-2513 18 p.

    Bar-Ilan University

    Research output: Contribution to journal › Review article › peer-review

    Open Access

  • Targeting the Cargo Receptor TMED9 as a Therapeutic Strategy Against Brain Tumors

    Daoud Sarsour, A., Kinstlinger, S., Nizar, R., Amos, N., Arbeli, N., Kazimirsky, G., Bronshtein-Berger, I., Fried, I., Unger, R., Brodie, C. & Dvela-Levitt, M., 23 May 2025, In: Cells. 14, 11, 21 p., 772.

    Bar-Ilan University

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Cross-species modeling of muscular dystrophy in Caenorhabditis elegans using patient-derived extracellular vesicles

    Shalash, R., Levi-Ferber, M., Cohen, C., Dori, A., Brodie, C. & Henis-Korenblit, S., 1 Mar 2024, In: DMM Disease Models and Mechanisms. 17, 3, 10 p., dmm050412.

    Bar-Ilan University, Tel Aviv University

    Research output: Contribution to journal › Article › peer-review

    Open Access
View all 97 Research outputs