Personal profile
Research interests
BRIEF BIOSKETCH
- Position: Full Professor in the Chemistry department, Bar-Ilan University.
- Professional experience: Leading a research group focusing on drug development and diagnostics, involved in national and international collaborations both in academia and industry for the last 20 years.
- Education: MSc degree in Medicinal Chemistry (chemistry of carbohydrates) under the supervision of Prof. A. Nudelman/BIU; PhD in Organic Chemistry (chemistry of heterocycles)/BIU under the supervision of Prof. A. Hassner; Post-doctorate (chemistry of nucleosides and nucleotides, molecular modeling) under the supervision of Dr. K. Jacobson/NIH, MD, USA.
- Teaching experience: Courses in - Medicinal Chemistry, Biochemistry, Inorganic Chemistry, Modern Strategies in Drug Design, Bio-in-organic Chemistry, Bio-organic seminar, and Organic Chemistry Laboratory.
- Over 110 papers and 10 patents.
- Membership: Vice dean of Scool of advanced studies, Bar-Ilan U senate member, member of the Israel Prize committee (in the field of Chemistry and Physics), former head of the Chemistry department, former Rector’s advisor for promotion of women in academia; Member of the Board of Executives of the Israeli Chemical Society, MSc Degree committee, PhD Degree committee, Referee of the Israeli Science Foundation committee, Referee of the Fulbright Foundation, Departmental Teaching committee, Member of the University Appointment and Promotion committee.
- Prizes: Teva Prize for excellent young scientists; Juludan Prize (Technion) for the Application of Exact Sciences to Medicine; Shoham Prize for arts
Research:
Medicinal Chemistry – development of drugs for the treatment of - type II diabetes, glaucoma, Alzheimer’s disease, osteoarthritis, and inflammatory bowel diseases; Diagnostics – development of fluorescent probes for diagnostics of breast cancer; Purinergic receptors; nucleotide metabolizing enzymes; chemistry of nucleosides/nucleotides and nucleic acids.
Education/Academic qualification
PhD, Bar-Ilan University
Jan 1984 → Jan 1990
Award Date: 1 Jan 1990
PhD, Bar-Ilan University
… → Feb 2007
Master, Bar-Ilan University
… → Feb 2007
Research
- תחומי מחקר
- כימיה אורגנית
- כימיה תרופתית
- Fields of Interest
- Organic Chemistry
- Pharmaceutical Chemistry
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Collaborations and top research areas from the last five years
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Innovative Cyclic Nucleotides – Nucleoside 2′,3′-Seven-Membered Cyclic Diphosphonate Derivatives. Theoretical Feasibility, Synthesis, and Properties
Liberman, S., Bobot, L., Ben Daniel, H. T., Major, D. T. & Fischer, B., 26 Jun 2025, In: Chemistry - A European Journal.Research output: Contribution to journal › Article › peer-review
Open Access -
Regioselective N1-ribosylation of hydantoin: synthesis and properties of the first contracted uridine analog
Bsoul, O., Lampel, Y., Rofe, M., Pariente-Cohen, N., Timsit, C. & Fischer, B., 30 Jan 2025, In: Chemical Communications. 61, 11, p. 2281-2284 4 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Styryl quinolinium, process for their preparation and use thereof as fluorescent probes for imaging
Fischer, B. (Inventor), Saady, A. E. (Inventor), Shav-Tal, Y. (Inventor) & Varon, E. (Inventor), 21 Jan 2025, Patent No. US20220119349A1, 21 Oct 2021, Priority date 21 Oct 2021, Priority No. US17/507,028Research output: Patent
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Hydrolytic (in)stability of phosphate isosteres
Nassir, M., Isaak, A. & Fischer, B., 15 Dec 2022, In: European Journal of Medicinal Chemistry. 244, 114836.Research output: Contribution to journal › Article › peer-review
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The Synthesis of Nucleoside 2′,3′-Cyclic Monophosphate Analogs with Regio- and Stereospecificity
Nassir, M., Saady, A., Cohen, N. P. & Fischer, B., Nov 2021, In: Current Protocols. 1, 11, e287.Research output: Contribution to journal › Article › peer-review