Personal profile
Research interests
Epitranscriptome, RNA modifications, non-coding RNA, transcription regulation, cancer, metastasis, human disease. We are investigating RNA based regulatory mechanisms involved in health and disease, focusing on roles of non-coding RNAs and the epitranscriptome
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Dive into the research topics where Aldema Sas-Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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A sequence-specific RNA acetylation catalyst
Gamage, S. T., Manage, S. H., Sas-Chen, A., Nir, R., Burkhart, B. W., Jhulki, I., Link, C. N., Penikalapati, M. S., Jones, J. E., Iyer, L. M., Aravind, L., Santangelo, T. J., Schwartz, S. & Meier, J. L., 11 Apr 2025, In: Nucleic acids research. 53, 6, gkaf217.Tel Aviv University, Weizmann Institute of Science
Research output: Contribution to journal › Article › peer-review
Open AccessFile -
High-throughput detection of RNA modifications at single base resolution
Ron, K., Kahn, J., Malka-Tunitsky, N. & Sas-Chen, A., Jan 2025, In: FEBS Letters. 599, 1, p. 19-32 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Role of RNA modifications in cancer metastasis
Malka-Tunitsky, N. & Sas-Chen, A., Aug 2024, In: Current Opinion in Genetics and Development. 87, 102232.Research output: Contribution to journal › Review article › peer-review
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A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit
Rebelo-Guiomar, P., Pellegrino, S., Dent, K. C., Sas-Chen, A., Miller-Fleming, L., Garone, C., Van Haute, L., Rogan, J. F., Dinan, A., Firth, A. E., Andrews, B., Whitworth, A. J., Schwartz, S., Warren, A. J. & Minczuk, M., Dec 2022, In: Nature Communications. 13, 1, 14 p., 929.Tel Aviv University, Weizmann Institute of Science
Research output: Contribution to journal › Article › peer-review
Open Access -
Antisense pairing and SNORD13 structure guide RNA cytidine acetylation
Thalalla Gamage, S., Bortolin-Cavaillé, M.-L., Link, C., Bryson, K., Sas-Chen, A., Schwartz, S., Cavaillé, J. & Meier, J. L., Dec 2022, In: RNA. 28, 12, p. 1582-1596 15 p.Tel Aviv University, Weizmann Institute of Science
Research output: Contribution to journal › Article › peer-review
Open Access