Single cell transcriptomics: Methods and applications

Itamar Kanter, Tomer Kalisky

نتاج البحث: نشر في مجلةمقالة مرجعيةمراجعة النظراء

ملخص

Traditionally, gene expression measurements were performed on "bulk" samples containing populations of thousands of cells. Recent advances in genomic technology have made it possible to measure gene expression in hundreds of individual cells at a time. As a result, cellular properties that were previously masked in "bulk" measurements can now be observed directly. In this review we will survey emerging technologies for single cell transcriptomics, and describe how they are used to study complex disease such as cancer, as well as other biological phenomena such as tissue regeneration, embryonic development, and immune response.

اللغة الأصليةالإنجليزيّة
رقم المقال53
دوريةFrontiers in Oncology
مستوى الصوت5
رقم الإصدارFEB
المعرِّفات الرقمية للأشياء
حالة النشرنُشِر - 2015

All Science Journal Classification (ASJC) codes

  • !!Oncology
  • !!Cancer Research

بصمة

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