Endocannabinoids: The lipid effectors of metabolic regulation in health and disease

Tony Jourdan, Pascal Degrace, Isabel González-Mariscal, Gergo Szanda, Joseph Tam

نتاج البحث: فصل من :كتاب / تقرير / مؤتمرفصلمراجعة النظراء

ملخص

Endocannabinoids (eCBs) are endogenous lipid mediators that activate the cannabinoid-1 and -2 receptors (CB1R and CB2R, respectively), which mediate the effects of marijuana. The endocannabinoid system (ECS), consisting of eCBs, their receptors and the enzymes involved in their biosynthesis and degradation, is present in the central nervous system as well as in various peripheral tissues. The present chapter discusses accumulating evidence indicating that the ECS is involved in modulating energy homeostasis, adipose tissue metabolism, glucose and insulin balance as well as hepatic lipogenesis in health and metabolic diseases.

اللغة الأصليةإنجليزيّة أمريكيّة
عنوان منشور المضيفLipid Signaling and Metabolism
ناشرElsevier
الصفحات297-320
عدد الصفحات24
رقم المعيار الدولي للكتب (الإلكتروني)9780128194041
المعرِّفات الرقمية للأشياء
حالة النشرنُشِر - 1 يناير 2020

All Science Journal Classification (ASJC) codes

  • !!General Biochemistry, Genetics and Molecular Biology

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